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Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient (O2 Fraction)

This study is currently recruiting participants.
Verified November 2012 by Swedish Medical Center
Sponsor:
Information provided by (Responsible Party):
Swedish Medical Center
ClinicalTrials.gov Identifier:
NCT01513213
First received: January 5, 2012
Last updated: November 16, 2012
Last verified: November 2012
History of Changes

January 5, 2012
November 16, 2012
October 2011
October 2013   (final data collection date for primary outcome measure)
Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient. [ Time Frame: At least 2 hours ] [ Designated as safety issue: No ]
Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.
Repeatedly measure the level of carbon dioxide in a patient's blood during surgery. [ Time Frame: At least 2 hours ] [ Designated as safety issue: No ]
Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.
Complete list of historical versions of study NCT01513213 on ClinicalTrials.gov Archive Site
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Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient
Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.
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Observational
Observational Model: Case-Only
Time Perspective: Cross-Sectional
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Non-Probability Sample

Adults age 18 to 65 scheduled for a surgical procedure that will last at least two hours and for whom arterial cannulation and at least two arterial blood gas analyses are planned during the surgery.
Neurosurgery
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
50
October 2013
October 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age 18 to 65.
  • Scheduled for surgical procedure that will last at least 2 hours.
  • Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.
  • At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria:

  • No arterial cannulation is necessary or planned for the procedure.
Both
18 Years to 65 Years
No
Contact: Arthur M Lam, MD, FRCPC 206-320-2776 arthur.lam@swedish.org
United States
 
NCT01513213
5119S-11
No
Swedish Medical Center
Swedish Medical Center
Not Provided
Principal Investigator: Arthur M Lam, MD, FRCPC Swedish Medical Center
Swedish Medical Center
November 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP