Assessing Fermentability of a Dietary Fiber (FCHO)

• The changes in postprandial glucose concentrations after consuming test meals with FCHO drink compared to placebo drink [ Time Frame: 8 hours ] [ Designated as safety issue: No ]

  FCHO will be incorporated in a breakfast meal and compared to the same meal without the FCHO. Subjects will be served a breakfast meal with FCHO or without FCHO in a randomly assigned sequence on two separate occasions (visit 1 and visit 2) under fasting conditions.

  Blood glucose will be measured before (fasting/baseline) and after breakfast test meal intake for 4hrs: 0, 30 min, 60 min, 120 min, and 240 min and then again after the light lunch meal at 30, 60, 90, 120 post lunch.

• The tolerability of treatments over 7 days [ Time Frame: 7 days ] [ Designated as safety issue: No ]
  After the in-lab study day (visit 1 and visit 2), subjects will go home with the test beverage packs to be consumed daily for 7 days. Subjects will maintain diaries to ensure daily consumption and on day 7 will be asked to complete a brief questionnaire related to gastrointestinal experiences during the week. Identical procedures will take place after both study days, except the assigned treatment will differ.

The objective of this study is to provide evidence for its fermentability of a dietary fiber and to collect information regarding potential health opportunities for glucose control as well as tolerability when being consumed over 7 days.

This study is designed as a randomized, 2-arm, treatment-controlled, within-subjects, 8-hour postprandial crossover study, utilizing a multiple sampling paradigm to evaluate fermentability and potential health opportunities for glucose control of a dietary fiber (FCHO) in healthy non-obese men and women. The study will include 2 - 8 h assessments following consumption of the FCHO drink or a placebo drink and will follow with a 7 day feeding period to assess tolerability.

• Dietary Supplement: A dietary fiber (FCHO)
  15 g twice per day in beverage
  Other Name: FCHO
• Dietary Supplement: Placebo
  Placebo drink
  Other Name: PCB

• Placebo Comparator: Placebo
  Placebo Beverage
  Intervention: Dietary Supplement: Placebo
• Active Comparator: A dietary fiber (FCHO)
  15g/BID
  Intervention: Dietary Supplement: A dietary fiber (FCHO)

Inclusion Criteria:

• 18 years of age or older
• BMI between 18.5 and 29.9 kg/m2, inclusive
• No clinical evidence of cardiovascular, metabolic, respiratory, renal, gastrointestinal, or hepatic disease
• No diabetes
• No Gastrointestinal issues

Exclusion Criteria:

• Pregnant and/or lactating or planning for pregnancy
• Allergies or intolerances to foods consumed in the study Fasting blood glucose > 125 mg/dL.
• Vegetarian
• Taking over the counter fiber supplements or other supplements that may interfere with the study procedures or endpoints
• Taking actively probiotics or purposely taking/ subscribing to a diet high in prebiotics.
• Taking prescription medications that may interfere with study procedures or endpoints (eg., antibiotics)
• Subjects with unusual dietary habits (e.g. pica)
• Actively losing weight or trying to lose weight (unstable body weight fluctuations of > 5 kg in a 60 day period)
• Excessive exercisers or trained athletes
• Addicted to drugs and/or alcohol
• Medically documented psychiatric or neurological disturbances
• Smokers (past smokers may be allowed if cessation is > 2 years)