Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2011 by National Taiwan University Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT01486693
First received: November 16, 2011
Last updated: December 5, 2011
Last verified: December 2011

November 16, 2011
December 5, 2011
October 2011
December 2011   (final data collection date for primary outcome measure)
Anterior chamber inflammation [ Time Frame: 4 weeks after starting treatment ] [ Designated as safety issue: No ]
anterior chamber cell grading based on slit lamp microscopy
Same as current
Complete list of historical versions of study NCT01486693 on ClinicalTrials.gov Archive Site
probability of relapse-free [ Time Frame: 2 years after treatment ] [ Designated as safety issue: No ]
Kaplan-Meier curve of relapse-free probability
Same as current
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Not Provided
 
Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis
Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis

The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in Cytomegalovirus (CMV) anterior uveitis.

The investigators will enroll 60 patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping from January 2006 to June 2011. All the patients (40 men, 20 women) were immunocompetent and diagnosed as symptomatic CMV infection. Their medical records will be reviewed, including demographic data as well as their ophthalmic and medical histories.

The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in CMV anterior uveitis.

Observational
Observational Model: Cohort
Time Perspective: Retrospective
Not Provided
Not Provided
Non-Probability Sample

40 men, 20 women, aged 40-80 years old

Anterior Uveitis
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
60
September 2012
December 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping. All the patients were immunocompetent and diagnosed as symptomatic CMV infection.

Exclusion Criteria:

  • Patients without positive results of the CMV PCR
  • Immunocompromised patients with positive results of the CMV PCR
Both
40 Years to 80 Years
No
Contact: I-Jong Wang, M.D. PhD 886-23123456 ext 65729 ijong@ntu.edu.tw
Taiwan
 
NCT01486693
201109016RC
No
National Taiwan University Hospital
National Taiwan University Hospital
Not Provided
Principal Investigator: I-Jong Wang, M.D PhD National Taiwan University Hospital
National Taiwan University Hospital
December 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP