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Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2012 by University of Manitoba.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
GlaxoSmithKline
Information provided by (Responsible Party):
Dr. Anand Kumar, University of Manitoba
ClinicalTrials.gov Identifier:
NCT01485237
First received: December 1, 2011
Last updated: July 3, 2012
Last verified: July 2012

December 1, 2011
July 3, 2012
October 2009
December 2010   (final data collection date for primary outcome measure)
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Not Provided
Complete list of historical versions of study NCT01485237 on ClinicalTrials.gov Archive Site
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Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization
Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization

The main purpose of this study is to review the resource utilization of severe adult H1N1 pneumonia undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO, HFO) in critically ill patients in Winnipeg. Secondary objectives include, comparison of resource utilization to other similar disorders (viral pneumonia, bacterial pneumonia, septic shock, ARDS). The investigators will also look at the percentage of patients that required ICU care as compared to those who could be cared for on medical wards. The investigators will determine the resources used by both groups and compare. Finally the investigators will record the frequency of chronic comorbidities in hospitalized adult H1N1 patients.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Retrospective
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Non-Probability Sample

Patients with severe adult H1N1 pneumonia undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO, HFO) in critically ill patients in Winnipeg. Patients with other similar disorders (viral pneumonia, bacterial pneumonia, septic shock, ARDS)that may require some of the same treatments.

Novel H1N1 Influenzal Acute Respiratory Infection
Other: We will compare the resources used by both groups
The main purpose of this study is to review the resource utilization. Secondary objectives include, comparison of resource utilization to other similar disorders (viral pneumonia, bacterial pneumonia, septic shock, ARDS). We will also look at the percentage of patients that required ICU care as compared to those who could be cared for on medical wards. We will determine the resources used by both groups and compare. Finally we will record the frequency of chronic comorbidities in hospitalized adult H1N1 patients.
  • Severe H1N1 pneumonia in adult patients
    Severe adult H1N1 pneumonia patients undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO, HFO)in Winnipeg
    Intervention: Other: We will compare the resources used by both groups
  • Severe pneumonia in adults not H1N1
    Patients admitted to the hospital and/or ICU with viral pneumonia, bacterial pneumonia, septic shock, ARDS in Winnipeg
    Intervention: Other: We will compare the resources used by both groups
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
400
December 2012
December 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. > 18years,
  2. Suspected or confirmed influenza (Appendix A)
  3. Requirement for ICU admission due to respiratory distress or critical illness defined as one of:a) Inspired oxygen need of >50% for at least 4 hours (For FiO2 for non-intubated patients see Appendix B) b) mechanical ventilation c) Patient is receiving inotrope or vasopressor

Exclusion Criteria:

1. Age less than 18 years

Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Canada
 
NCT01485237
pandemic001, H2009:175
No
Dr. Anand Kumar, University of Manitoba
University of Manitoba
GlaxoSmithKline
Principal Investigator: Anand Kumar, MD Health Sciences Centre, Winnipeg
University of Manitoba
July 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP