Text Size

Intelligence Changes Following Minor Surgery

This study is currently recruiting participants.
Verified March 2012 by RenJi Hospital
Sponsor:
Collaborator:
Shanghai Children's Medical Center
Information provided by (Responsible Party):
diansan su, RenJi Hospital
ClinicalTrials.gov Identifier:
NCT01483313
First received: October 13, 2011
Last updated: March 7, 2012
Last verified: March 2012
History of Changes

October 13, 2011
March 7, 2012
November 2011
October 2012   (final data collection date for primary outcome measure)
Wechsler Intelligence Scale for Children [ Time Frame: Average 5 years after surgery ] [ Designated as safety issue: No ]
Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.
Same as current
Complete list of historical versions of study NCT01483313 on ClinicalTrials.gov Archive Site
Achenbach Child Behavior Checklist [ Time Frame: Average 5 years after surgery ] [ Designated as safety issue: No ]
Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.
Same as current
Not Provided
Not Provided
 
Intelligence Changes Following Minor Surgery
Intelligence Performance in Adolescence After Early Exposure to Anesthesia and Minor Surgery

Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted. In present study, the investigators examined the association between early exposure to anesthesia and surgery for minor surgery and intelligence changes in adolescence using the Wechsler Intelligence Scale for Children.
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Probability Sample

The investigators would like chose the Children who undergone minor surgery in Renji hospital 4-6years ago and their friends who never had any surgery.
  • Hypospadia
  • Phimosis
  • Inguinal Hernia
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
800
December 2012
October 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. Born from 1995
  2. Male
  3. Parents or guardian agree to attend this study
  4. Undergone minor surgery (Repair of hypospadias, phimosiectomy, cryptorchidectomy or cryptorchidopexy and repair of inguinal hernia)
  5. Children who scarify the No.1 to No.3 but no experience of any surgery.
  6. Those who undergone minor surgery in Renji Hospital 4-6years ago.

Exclusion Criteria:

  1. Any congenital central nervous system diseases
  2. Any congenital heart diseases
  3. Any congenital dysgnosia
  4. Birth weight less than 2kg
  5. Ever been hypoxic encephalopathy when birth
Male
6 Years to 16 Years
Yes
Contact: Diansan Su, M.D., Ph.D. 0086-1381-7294-179 Diansansu@yahoo.com
China
 
NCT01483313
RenJiH-20111005
Yes
diansan su, RenJi Hospital
RenJi Hospital
Shanghai Children's Medical Center
Principal Investigator: Diansan Su, M.D., Ph.D RenJi Hospital
RenJi Hospital
March 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP