Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Liliane Barbosa da Silva Passos, Federal University of Uberlandia
ClinicalTrials.gov Identifier:
NCT01482429
First received: November 27, 2011
Last updated: January 27, 2013
Last verified: January 2013

November 27, 2011
January 27, 2013
January 2011
January 2012   (final data collection date for primary outcome measure)
  • Mortality [ Time Frame: length of ICU stay (days) ] [ Designated as safety issue: Yes ]
  • Duration of Weaning From Mechanical Ventilation [ Time Frame: days ] [ Designated as safety issue: Yes ]
  • Duration of Mechanical Ventilation [ Time Frame: days ] [ Designated as safety issue: Yes ]
  • Length of Intensive Care Unit Stay [ Time Frame: days ] [ Designated as safety issue: Yes ]
  • Duration of weaning from mechanical ventilation [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
  • Duration of mechanical ventilation [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
Complete list of historical versions of study NCT01482429 on ClinicalTrials.gov Archive Site
Not Provided
  • Length of intensive care unit stay [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
  • Length of hospital stay [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
  • mortality [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
  • Ventilator-associated pneumonia incidence [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]
Not Provided
Not Provided
 
Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Implantation of a Multidisciplinary Ventilator-weaning Protocol in a Intensive Care Unit of Teaching Hospital of Federal University of Uberlandia

Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers.

The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.

Not Provided
Interventional
Not Provided
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
  • Weaning Failure
  • Complication of Respirator [Ventilator]
Other: Multidisciplinary weaning-ventilator protocol
We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.
Other Name: Weaning-ventilator protocol
  • Experimental: Protocol-directed
    Discontinuation of ventilation was based in multidisciplinary protocol.
    Intervention: Other: Multidisciplinary weaning-ventilator protocol
  • No Intervention: Usual care
    Discontinuation of ventilation was left entirely to the discretion of the physicians.
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
235
January 2012
January 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • remain in mechanical ventilation for more than 24 hours
  • begin weaning from mechanical ventilation

Exclusion Criteria:

  • admitted in the unit already in weaning from mechanical ventilation
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT01482429
Desmame
Yes
Liliane Barbosa da Silva Passos, Federal University of Uberlandia
Federal University of Uberlandia
Not Provided
Principal Investigator: Liliane Barbosa da Silva Passos Federal University of Uberlandia
Study Chair: Thulio Marquez Cunha Federal University of Uberlandia
Study Chair: Carlos Henrique Alves de Rezende, MD Federal University of Uberlandia
Federal University of Uberlandia
January 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP