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Contingency Management for Persons With Severe Mental Illness

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
University of Connecticut Health Center
ClinicalTrials.gov Identifier:
NCT01478815
First received: November 21, 2011
Last updated: January 15, 2013
Last verified: December 2012

November 21, 2011
January 15, 2013
December 2011
August 2012   (final data collection date for primary outcome measure)
longest continuous period of cocaine abstinence [ Time Frame: Week 8 ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01478815 on ClinicalTrials.gov Archive Site
other drug use and psychosocial problems [ Time Frame: Week 8 ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Contingency Management for Persons With Severe Mental Illness
Contingency Management for Persons With Severe Mental Illness

Contingency management is efficacious for treating cocaine abuse, but contingency management interventions have rarely been applied to patients with severe and persistent mental health problems. This pilot project will estimate effect sizes of contingency management for reducing cocaine use in patients receiving psychiatric care at a large community based mental health program. In total, 30 cocaine abusing patients will be randomized to one of two 8-week treatment conditions: standard care or standard care with contingency management. Patients in both conditions will provide breath and urine samples for toxicology testing twice per week. In the contingency management condition, patients will receive the opportunity to win prizes for submitting cocaine negative urine samples. The investigators expect that patients receiving contingency management will evidence reductions in cocaine use and may show improvements in psychiatric symptoms and psychosocial functioning relative to patients in standard care. Effect size estimates obtained from this study will be used to guide larger scale and longer duration evaluations of contingency management for dually diagnosed patients.

Not Provided
Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Substance Abuse
  • Behavioral: contingency management
    Participants will receive the opportunity to win prizes for submitting cocaine negative urine samples.
  • Other: Standard Care
    Standard Care
  • Placebo Comparator: Standard Care
    Intervention: Other: Standard Care
  • Experimental: Contingency management for abstinence from drugs
    Intervention: Behavioral: contingency management
Petry NM, Alessi SM, Rash CJ. A randomized study of contingency management in cocaine-dependent patients with severe and persistent mental health disorders. Drug Alcohol Depend. 2013 Jun 1;130(1-3):234-7. doi: 10.1016/j.drugalcdep.2012.10.017. Epub 2012 Nov 20.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
19
August 2012
August 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • age 18 years or older
  • meet DSM-IV criteria for cocaine abuse or dependence
  • English speaking
  • pass a brief quiz regarding study procedures to ensure understanding of the informed consent process.

Exclusion Criteria:

  • dementia
  • in recovery from pathological gambling
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01478815
12-070-3, P30DA023918
Yes
University of Connecticut Health Center
University of Connecticut Health Center
National Institute on Drug Abuse (NIDA)
Principal Investigator: Nancy M Petry, Ph.D. University of Connecticut Health Center
University of Connecticut Health Center
December 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP