PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Bojan Rode, Sisters of Mercy University Hospital
ClinicalTrials.gov Identifier:
NCT01478217
First received: November 20, 2011
Last updated: November 22, 2011
Last verified: November 2011

November 20, 2011
November 22, 2011
October 2009
November 2011   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01478217 on ClinicalTrials.gov Archive Site
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PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
Positive End-expiratory Pressure Induced Lung Recruitment -Comparison Between Ultrasonographic Assessment and Lower Inflection Point Assessment on the Pressure -Volume Loop

The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.

Sedated and sometimes temporary relaxed patients with ALI/ARDS on mechanical ventilation in semirecumbent position are included. Lower inflection point on pressure volume loop on ventilator Draeger Evita 4 with low continuous flow on volume controlled ventilation is measured with zero PEEP. Transthoracic lung ultrasound with linear probe is proceed on both hemithoraces when mechanical ventilation based on measured PEEP is started. We compare if real lung recruitment seen by ultrasound is the same as predicted by lower inflection point.

The procedure is a part of routine everyday respiratory monitoring in our unit.

Observational
Observational Model: Case Control
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Probability Sample

intensive care patients

Acute Respiratory Distress Syndrome
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Bouhemad B, Brisson H, Le-Guen M, Arbelot C, Lu Q, Rouby JJ. Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med. 2011 Feb 1;183(3):341-7. Epub 2010 Sep 17.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
17
November 2011
November 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • patients with diffuse ALI/ARDS on mechanical ventilation with visible lower inflection point on dynamic P-V loops

Exclusion Criteria:

  • preexisting parenchymal or pleural lung disease
Both
16 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Croatia
 
NCT01478217
Vinogradska29
No
Bojan Rode, Sisters of Mercy University Hospital
Sisters of Mercy University Hospital
Not Provided
Principal Investigator: Bojan Rode, M.D.
Sisters of Mercy University Hospital
November 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP