Volumetric Monitoring in Major Lung Surgery (EVLW-PNEUMO)

This study has been completed.
Sponsor:
Collaborators:
Regional hospital of Arkhangelsk
University of Tromso
Information provided by (Responsible Party):
Vsevolod V. Kuzkov, Northern State Medical University
ClinicalTrials.gov Identifier:
NCT01455766
First received: October 17, 2011
Last updated: September 4, 2012
Last verified: September 2012

October 17, 2011
September 4, 2012
June 2005
February 2008   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01455766 on ClinicalTrials.gov Archive Site
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Volumetric Monitoring in Major Lung Surgery
Pulmonary Edema Following Major Thoracic Resections: a Value of Perioperative Volumetric Monitoring

The hypothesis of this observational single-center clinical study was to explore the volumetric hemodynamic monitoring in the perioperative period in major and risky thoracic intervention. The investigators monitored the changes in the volumes of blood in the central vessels and heart chambers as well as a volume of fluid in pulmonary tissue (i. e. extravascular lung water).

The goal of this observational study is to investigate into changes in volumetric hemodynamic parameters obtained with a technique of transpulmonary indicator dilution after major thoracic intervention, including pneumonectomy and lobar resections. The important parameters of hemodynamics were monitored throughout the intervention and 48 hrs postoperatively, including extravascular lung water index, global end-diastolic volume index, etc.

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

Blood plasma for non-specified additional retrospective tests.

Non-Probability Sample

The study population includes the patients scheduled for extended thoracic resections (lobar resection and pneumonectomy) due to bronchial cancer or severe destructive pulmonary infection (abscess and/or pneumonia).

  • Pneumonectomy
  • Acute Pulmonary Edema
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
November 2011
February 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Informed consent
  • Age above 18 and below 80
  • Confirmed malignant bronchial neoplasm or
  • Destructive pulmonary infection

Exclusion Criteria:

  • Pregnant
  • Severe pulmonary hypertension
  • Pulmonary tuberculosis
  • Severe occlusive atherosclerosis of lower extremities
Both
18 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
Russian Federation
 
NCT01455766
2005-2011
No
Vsevolod V. Kuzkov, Northern State Medical University
Northern State Medical University
  • Regional hospital of Arkhangelsk
  • University of Tromso
Principal Investigator: Vsevolod V. Kuzkov, MD, PhD Northern State Medical University
Principal Investigator: Mikhail M. Orlov, MD Regional hospital of Arkhangelsk
Study Chair: Mikhail Y. Kirov, MD, PhD Northern State Medical University
Study Director: Lars J. Bjertnaes, MD, PhD University of Trmsoe, Tromsoe, Norway
Northern State Medical University
September 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP