Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2011 by Medical University of Vienna.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Markus Zeitlinger, Medical University of Vienna
ClinicalTrials.gov Identifier:
NCT01414959
First received: August 10, 2011
Last updated: September 5, 2011
Last verified: September 2011

August 10, 2011
September 5, 2011
August 2011
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Complete list of historical versions of study NCT01414959 on ClinicalTrials.gov Archive Site
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Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients
Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

Methods: microdialysis, blood sampling, bronchoalveolar lavage

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

plasma broncheoalvoeolar lavage microdialysates

Non-Probability Sample

intubated patients, intensive care

  • Pneumonia
  • Abdominal Infection
  • Urinary Tract Infection
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
16
July 2013
Not Provided

Inclusion Criteria:

  • endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection

Exclusion Criteria:

  • allergy to doripenem, hemodialysis
Both
18 Years and older
No
Contact: markus zeitlinger, md 0043140400 ext 2981 markus.zeitlinger@meduniwien.ac.at
Austria
 
NCT01414959
Dori_MD_ICU
No
Markus Zeitlinger, Medical University of Vienna
Medical University of Vienna
Not Provided
Principal Investigator: Markus Zeitlinger, MD Medical Universit of Vienna
Medical University of Vienna
September 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP