The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by:
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01384136
First received: June 27, 2011
Last updated: NA
Last verified: June 2011
History: No changes posted

June 27, 2011
June 27, 2011
June 2011
June 2015   (final data collection date for primary outcome measure)
Not Provided
Not Provided
No Changes Posted
Not Provided
Not Provided
Not Provided
Not Provided
 
The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies
The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

The telomere system stabilizes the chromosomes. Telomeres are shortened during senescence, in cases of genetic instability and secondary to stress.

The investigators aim is to study the telomere system in cord blood and in the placenta immediately after the delivery in pregnancies defined as high risk pregnancies following sterss events such as placental insufficiency, preeclampsia, diabetes.

The investigators intend to compare the telomere system in maternal blood to cord blood and to placental biopsies and to study the influence of different stressogenes on this system.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Cross-Sectional
Not Provided
Not Provided
Non-Probability Sample

High risk pregnancies, third trimester, after the delivery/

  • Telomere Length
  • Mechanisms of Telomter Homeostasis
  • High Risk Pregnancies
Not Provided
  • High risk pregnancy
  • |Control - Normal low risk pregnancies
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
100
June 2015
June 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Third trimester post delivery
  • Intrauterine growth restriction
  • Preeclampsia
  • Diabetes
  • Control - low risk normal pregnancies

Exclusion Criteria:

  • Patients who do not want to participate
  • Known HIV or Hepatitis
Female
18 Years to 45 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Israel
 
NCT01384136
036-2011 MMC
Yes
Tal Biron-Shental, Meir Medical Center, Kfar Saba, Israel
Meir Medical Center
Not Provided
Not Provided
Meir Medical Center
June 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP