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Aggressive Prostate Cancers in Elderly Patients

This study has been completed.
Sponsor:
Information provided by:
Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT01347476
First received: April 29, 2011
Last updated: May 18, 2011
Last verified: May 2011
History of Changes

April 29, 2011
May 18, 2011
January 2010
October 2010   (final data collection date for primary outcome measure)
biochemical recurrences (BCR) [ Time Frame: 5 year-BCR ] [ Designated as safety issue: No ]
BCR was defined as two consecutive increasing PSA values of more than 0.2 ng/mL
Same as current
Complete list of historical versions of study NCT01347476 on ClinicalTrials.gov Archive Site
pathologic outcomes [ Time Frame: postoperative 1 week ] [ Designated as safety issue: No ]
biopsy or pathologic Gleason scores, mean percent of positive cores and tumor volume percent, Extracapsular extension and seminal vesicle invasion
Same as current
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Aggressive Prostate Cancers in Elderly Patients
Patients Aged More Than 70 Had More Aggressive Prostate Cancers and Higher Risk of Biochemical Recurrence in Korea

Patients aged 70 years or older had a higher possibility of high risk cancer than younger patients.

Patients aged 70 years or older had a higher risk of advanced prostate cancer and shorter BCR-free survival than younger ones. Definite treatment of clinically localized prostate cancer should be actively considered in well-selected healthy patients older than 70 years.
Observational
Observational Model: Case Control
Time Perspective: Retrospective
Not Provided
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Non-Probability Sample

Men who underwent radical prostatectomy for the treatment of clinically localized prostate cancer
Prostatic Neoplasms
Not Provided
  • patients older than 70 years
  • patients 70 years or younger
Kim JK, Cho SY, Jeong CW, Lee SB, Ku JH, Hong SK, Byun SS, Kwak C, Him HH, Lee SE, Jeong H. Patients aged more than 70 had higher risk of locally advanced prostate cancers and biochemical recurrence in Korea. BJU Int. 2012 Aug;110(4):505-9. doi: 10.1111/j.1464-410X.2011.10927.x. Epub 2012 Feb 7. PubMed PMID: 22314007.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1333
October 2010
October 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • clinically localized prostate cancer
  • good health status
  • follow-up period more than 12 months

Exclusion Criteria:

  • insufficient clinical data
  • poor health status
  • clinically advanced prostate cancer
Male
40 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT01347476
old age prostate, elderly pts with high risk CaP
Yes
Seoul National University Boramae Hospital
Seoul National University Hospital
Not Provided
Principal Investigator: Sung Yong Cho, M.D. Seoul National University Hospital
Seoul National University Hospital
May 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP