Acute Cardiovascular Effects of Cigarette Smoking

This study has been completed.
Sponsor:
Information provided by:
Andhra Medical College
ClinicalTrials.gov Identifier:
NCT01346956
First received: May 2, 2011
Last updated: May 3, 2011
Last verified: January 2003

May 2, 2011
May 3, 2011
July 2002
August 2002   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01346956 on ClinicalTrials.gov Archive Site
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Acute Cardiovascular Effects of Cigarette Smoking
Acute Cardiovascular Effects of Cigarette Smoking

Twenty healthy smokers will be subjected to measurement of Pulse, Blood Pressure, electrocardiogram (ECG) and Echo at baseline and after smoking a cigarette. The measurements will be compare for any cardiovascular effects of a cigarette smoking on these parameters.

Twenty male persons habituated to smoking (at least 5 cigarettes/day) will be recruited after an informed consent. Healthy persons with no systemic illness will be included. After a history and a routine examination, subjects will be asked to abstain from smoking for 3 hours and then their pulse, BP, ECG and echo recorded. The measurements will be repeated after 15 min. and the average of these two taken as baseline readings. Then, they will be asked to smoke a cigarette and the measurements taken again. Special focus will be on Doppler measures of left ventricular (LV) function. The measurements are repeated immediately and at 5,10 and 15 min. The data will be analyzed for any cardiovascular effects of smoking a cigarette. Chi square test for proportions and t-test for means will be done. A p value < 0.05 will be taken as significant.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample

Twenty healthy male smokers

Smoking
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
20
August 2002
August 2002   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy male smokers (at least 5 cigarettes /day) >18 years old.

Exclusion Criteria:

  • Any cardiac or respiratory or systemic illness,including hypertension.
Male
18 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
India
 
NCT01346956
02AMCRAVSAND07
No
Ravi Venkatachelam Chitrapu, Andhra Medical College
Andhra Medical College
Not Provided
Principal Investigator: Venkatachelam R Chitrapu, MD DM Andhra Medical College
Andhra Medical College
January 2003

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP