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Effect of Short-term Chinese Tea-flavor Liquor Consumption (ESTCTFLC)

This study has been completed.
Sponsor:
Collaborator:
Guizhou Meijiao Co., Ltd
Information provided by:
Zhejiang University
ClinicalTrials.gov Identifier:
NCT01294995
First received: February 11, 2011
Last updated: NA
Last verified: October 2010
History: No changes posted

February 11, 2011
February 11, 2011
October 2010
November 2010   (final data collection date for primary outcome measure)
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No Changes Posted
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Effect of Short-term Chinese Tea-flavor Liquor Consumption
Phase 1 Study of Chinese Tea-flavor Liquor

Human studies of Chinese liquor are sparse. The investigators hypothesize that short-term Chinese Tea-flavor liquor (TFL) consumption may be beneficial to inflammation biomarkers and CVD risk factors. Guizhou Meijiao Liquor (GML) is a traditional Chinese liquor, fermented from sorghum, corn, sticky rice, wheat and rice, while TFL is a novel Chinese liquor fermented from above 5 grains plus green tea.

Forty-five volunteers(23 males, 22 females) were selected to participate a paralleled randomized trial drinking 30 mL two kinds of Chinese liquors: TFL and GML respectively with meal every day for 28 days. Serums of volunteers were collected for analyzing serum lipids, inflammation biomarkers and CVD risk factors.

TFL could significantly decrease systolic blood pressure of males, but increase diastolic blood pressure of females. TFL could also decreased blood lipid of volunteers, especially for females. Both liquor significantly decrease serum uric acid and glucose in males and females. The effect of the two liquors on inflammation biomarkers were complicated and needs further research work.

TFL may possess more beneficial effect on CVD risk factors than GML probably because of the special fermentation products of green tea with other grains.

Not Provided
Interventional
Phase 1
Allocation: Randomized
Endpoint Classification: Bio-availability Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Cardiovascular Diseases
  • Dietary Supplement: Tea-flavor Liquor
    30 mL of Tea-flavor Liquor(45% alcohol content)
  • Dietary Supplement: Guizhou Meijiao Liquor
    30 mL of Guizhou Meijiao Liquor (45% alcohol content)
  • Experimental: Tea-flavor Liquor, taken with meal
    including 12 males and 11 females
    Intervention: Dietary Supplement: Tea-flavor Liquor
  • Placebo Comparator: Guizhou Meijiao Liquor, taken with meal
    including 11 males and 11 females
    Intervention: Dietary Supplement: Guizhou Meijiao Liquor
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
45
November 2010
November 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy male and female volunteers

Exclusion Criteria:

  • Subjects with a history of liver disease, diabetes, or heart disease
  • Smokers
Both
23 Years to 28 Years
Yes
Contact information is only displayed when the study is recruiting subjects
China
 
NCT01294995
ST Chinese liquor study
Yes
Department of Food Science and Nutrition
Zhejiang University
Guizhou Meijiao Co., Ltd
Not Provided
Zhejiang University
October 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP