Evaluation of the Proliferative Activities of Insulin Analogues in Primary Human Tumor Cells

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2012 by Meir Medical Center.
Recruitment status was  Available
Sponsor:
Collaborator:
Tel Aviv University
Information provided by (Responsible Party):
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01267461
First received: December 27, 2010
Last updated: August 9, 2012
Last verified: August 2012

December 27, 2010
August 9, 2012
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Complete list of historical versions of study NCT01267461 on ClinicalTrials.gov Archive Site
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Evaluation of the Proliferative Activities of Insulin Analogues in Primary Human Tumor Cells
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Recently the general medical literature has become aware that the use of certain long-acting insulin analogues could potentially increase cancer risk.During the last few years the investigators group generated information of both scientific and clinical relevance on the proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is to evaluate the hypothesis that the proliferative and signalling activities elicited by insulin analogues may have a impact on tumor behavior. In this study the investigators will asses the biological actions of insulin analogs in primary tumor cells of endometrial and colon cancer.

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Expanded Access
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  • Endometrial Cancer
  • Colon Cancer
Other: Tissue sample from tumor
Endometrial cancer specimens will be obtained from patients operated and treated at the Gynecologic Oncology Unit at Meir Medical Center. Colon cancer specimens will be obtained from patients that underwent colonoscopy at the Gastrointestinal Department at Meir Medical Center.
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
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Inclusion Criteria:

  • Patients with Endometrial and Colon Cancer

Exclusion Criteria:

  • None
Female
18 Years to 90 Years
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Contact: Ilan Bruchim, MD 972-9-7472561 ilan.bruchim@clalit.org.il
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NCT01267461
0015-10-MMC
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Meir Medical Center
Meir Medical Center
Tel Aviv University
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Meir Medical Center
August 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP