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Resistance Exercise in Healthy Men

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Lex Verdijk, Maastricht University Medical Center
ClinicalTrials.gov Identifier:
NCT01220037
First received: October 7, 2010
Last updated: October 25, 2013
Last verified: October 2013

October 7, 2010
October 25, 2013
April 2010
September 2011   (final data collection date for primary outcome measure)
  • Muscle fiber myonuclear and stem cell content [ Time Frame: baseline ] [ Designated as safety issue: No ]
  • Muscle fiber myonuclear and stem cell content [ Time Frame: 12 hours after a single bout of resistance type exercise ] [ Designated as safety issue: No ]
  • Muscle fiber myonuclear and stem cell content [ Time Frame: 24 hours after a single bout of resistance type exercise ] [ Designated as safety issue: No ]
  • Muscle fiber myonuclear and stem cell content [ Time Frame: 48 hours after a single bout of resistance type exercise ] [ Designated as safety issue: No ]
  • Muscle fiber myonuclear and stem cell content [ Time Frame: 72 hours after a single bout resistance type exercise ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01220037 on ClinicalTrials.gov Archive Site
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Resistance Exercise in Healthy Men
The Effect of Age and Dietary Protein Intake on Myocellular Characteristics Following a Single Bout of Resistance Exercise in Healthy Men

In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
  • Single Bout of Resistance Type Exercise
  • Standardized Diet
Behavioral: Adhere to a specific standardized diet for 4 days
24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.
  • Experimental: Young regular diet
    During the time of the study this group will adhere to a standardized regular diet.
    Intervention: Behavioral: Adhere to a specific standardized diet for 4 days
  • Experimental: Young low protein diet
    During the time of the study this group will adhere to a standardized low protein diet.
    Intervention: Behavioral: Adhere to a specific standardized diet for 4 days
  • Experimental: Young high protein
    During the time of the study this group will adhere to a standardized high protein diet.
    Intervention: Behavioral: Adhere to a specific standardized diet for 4 days
  • Experimental: Elderly
    During the time of the study this group will adhere to a standardized high protein diet
    Intervention: Behavioral: Adhere to a specific standardized diet for 4 days
Snijders T, Verdijk LB, McKay BR, Smeets JS, van Kranenburg J, Groen BB, Parise G, Greenhaff P, van Loon LJ. Acute dietary protein intake restriction is associated with changes in myostatin expression after a single bout of resistance exercise in healthy young men. J Nutr. 2014 Feb;144(2):137-45. doi: 10.3945/jn.113.183996. Epub 2013 Dec 4.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
34
December 2011
September 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • healthy men between the ages of 18-30 or 70-85 years

Exclusion Criteria:

  • Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.
Male
18 Years to 85 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Netherlands
 
NCT01220037
MEC 09-3-080
No
Lex Verdijk, Maastricht University Medical Center
Maastricht University Medical Center
Not Provided
Not Provided
Maastricht University Medical Center
October 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP