Gastroenteritis From Rotavirus Infection in Brazilian Children Less Than 5 Years of Age (Study V260-031 AM1).

• The Number of Hospitalizations for Diarrhea in Children up to 5 Years of Age [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  The total number of hospitalizations for diarrhea in children up to 5 years of age in the 4 Brazilian hospital research centers was reported. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
• The Percentage of Hospitalizations for Diarrhea in Children up to 5 Years of Age [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  The percentage of total hospitalizations for children up to 5 years of age in the 4 Brazilian hospital research centers that were for diarrhea. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
• The Geographic Distribution of Hospitalizations for Diarrhea That Are Caused by Rotavirus [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. For each geographic location, the number of hospitalizations for diarrhea that was caused by rotavirus was reported.
• The Percentage of Hospitalizations for Diarrhea That Are Caused by Rotavirus [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. The number of hospitalizations for diarrhea from rotavirus infection was divided by the total number of hospitalizations for diarrhea in the 4 hospital research centers.
• The Number of Hospitalizations for Diarrhea That Are Caused by Rotavirus by Age Group [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period. The number of hospitalizations for diarrhea from rotavirus infection was reported for each age group.
• The Numbers of Participants Hospitalized for Diarrhea and Rotavirus-caused Diarrhea Per Month [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  Children up to 5 years of age hospitalized for diarrhea were tested for fecal rotavirus as determined by enzyme immunoassay. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
• The Duration of Hospitalization for Participants Enrolled in the Study [ Time Frame: From hospital admission to discharge ] [ Designated as safety issue: No ]
  The mean duration (days) of hospital stay for children up to 5 years of age hospitalized for diarrhea in the 4 Brazilian hospital research centers. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.
• The Number of Deaths in Hospitalized Participants Enrolled in the Study [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  The number of deaths among children up to 5 years of age hospitalized for diarrhea in the 4 Brazilian hospital research centers. Diarrhea was defined as the passage of 3 or more soft/liquid feces in a 24-hour period.

• The number of hospitalizations for diarrhea in children under 5 years of age. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The rate of hospitalizations caused by diarrhea in children under 5 years of age. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The distribution of hospitalizations per diarrhea caused by rotavirus. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The percentages of hospitalizations per diarrhea associated to rotavirus at the age groups of 0-3, 3-6, 6-12, 13 -24, 25-36, 37-48 and 49-60 months. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The percentage of hospitalizations associated to diarrhea caused by rotavirus. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The numbers and percentages of hospitalizations for diarrhea and rotavirus-caused diarrhea per month or week. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The average and range of hospitalization duration for hospitalized patients enrolled in the study. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
• The number and rate of deaths associated to hospitalized patients enrolled in the study. [ Time Frame: 1 year ] [ Designated as safety issue: No ]

This is a 1-year study evaluating hospitalizations and the medical care for the treatment of diarrhea from rotavirus infection in children < 5 years of age, conducted in four hospitals located in four Brazilian regions. A stool sample from each eligible child passing 3 or more loose stools or watery stools within a period of 24 hours and requiring hospitalization or rehydration therapy (oral or IV rehydration) will be tested for the presence of rotavirus, using standard laboratory procedures (ie, Enzyme Linked Ligand Sorbent Assay, or ELlSA) by all participating hospitals.

Children less than 5 years of age from four Brazilian cities with diarrhea attributed to rotavirus infection.

Inclusion Criteria:

• a child < 5 years of age being treated for acute gastroenteritis within 72 hours prior to evaluation in the study hospitals.
• outpatient children < 5 years of age submitted for treatment of acute gastroenteritis within 72 hours prior to evaluation in the study clinics.

Exclusion Criteria:

• none specified