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Eosinophil Markers and Development of Disease in Allergic Rhinitis

This study has been completed.
Sponsor:
Collaborator:
Aarhus University Hospital
Information provided by:
University of Aarhus
ClinicalTrials.gov Identifier:
NCT01192386
First received: August 30, 2010
Last updated: August 31, 2010
Last verified: August 2010

August 30, 2010
August 31, 2010
May 2010
May 2010   (final data collection date for primary outcome measure)
Asthma morbidity [ Time Frame: Single measurement - May 2010 ] [ Designated as safety issue: No ]
Patients are asked whether they have experienced asthmatic symptoms or have been disgnosed with asthma within the latest 15 years
Same as current
Complete list of historical versions of study NCT01192386 on ClinicalTrials.gov Archive Site
Rhinitis morbidity [ Time Frame: Single measurement - May 2010 ] [ Designated as safety issue: No ]
Patients are asked for current hayfever symptoms
Same as current
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Eosinophil Markers and Development of Disease in Allergic Rhinitis
Eosinophil Markers and Development of Disease in Allergic Rhinitis. A 15-year Follow-up of Patients With Grass Pollen Induced Hayfever.

Inflammatory proteins from eosinophil granulocytes in blood from patients with seasonal allergic hayfever have been shown to predict development of asthma at a six-year follow-up. This study is a 15-year follow-up of the same patients to verify earlier results and study disease development.

The study consists of a single visit at which patients fill in a questionnaire on actual hayfever and asthma symptoms as well as current treatment. Blood samples and nasal lavages are drawn and analysed for eosinophils as well as eosinophil cationic protein and tryptase. Spirometry is performed.

If patients use drugs which can interfere with results, ie. corticosteroids or beta-agonists, biochemistry and/or spirometry are omitted.

Observational
Not Provided
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Non-Probability Sample

Follow-up on participants in Allergic Rhinitis study 1995.

Seasonal Allergic Rhinitis
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
29
May 2010
May 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Participant in earlier study (1995)

Exclusion Criteria:

  • Treatment with any kind of corticosteroid within two months will exclude from study of inflammatory parameters
Both
Not Provided
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT01192386
RHINO2010
No
Ass. professor Lars Peter Nielsen, Department of Respiratory Research, Aarhus University Hospital
University of Aarhus
Aarhus University Hospital
Principal Investigator: Lars Peter Nielsen, MD Department of Respiratory Research, Aarhus University Hospital, DK-8000 Aarhus C, Denmark
University of Aarhus
August 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP