AssEssment of CoMorbidities & Atrial ArRhythmiA Burden In DuaL-Chamber PaceD Patients

The purpose of this study is to evaluate the incidence and evolution over-time of co-morbidities in a general dual-chamber pacemaker population through a 2 years follow-up.

The study will particularly focus on the number of patients moving to persistent Atrial Fibrillation as a function of pacing mode, pacing sites, and cumulative %Ap & %Vp, in a general dual-chamber pacemaker population through a 2 year follow-up.

Sub-analyses will be performed stratifying patients per medical history (etiology, co-morbidities, medical therapy, reasons of implant, primo-implant/replacement.

The sponsor plans the enrolment of a total of 2188 subjects in this clinical investigation.

Inclusion Criteria:

• Patient implanted (primo-implant, replacement, upgrade) with one of the devices listed in § 2.2 from less than two months.
• Patient has signed the consent to data treatment (according to the laws and regulations of the country in which the observation is performed)

Exclusion Criteria:

1. Contraindicated for cardiac pacing, according to the ESC and ACC/AHA/HRS guidelines
2. Permanent or persistent atrial tachyarrhythmia
3. Already included in another interventional clinical study
4. Life expectancy less than 24 months
5. Not available for routine follow-up visits.
6. Inability to understand the purpose of the study or refusal to cooperate
7. Under guardianship
8. Age of less than 18 years
9. Pregnancy (Women of childbearing potential should have a negative pregnancy test prior to enrollment)