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Lung Perfusion With Oxygenated Blood During Aortic Clamping (PulPer-001-Sch)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Arndt-H. Kiessling, Johann Wolfgang Goethe University Hospitals
ClinicalTrials.gov Identifier:
NCT01186510
First received: August 19, 2010
Last updated: June 3, 2013
Last verified: June 2013

August 19, 2010
June 3, 2013
August 2010
November 2012   (final data collection date for primary outcome measure)
Inflammatory marker [ Time Frame: 5 days ] [ Designated as safety issue: No ]
Inflammatory marker
Complete list of historical versions of study NCT01186510 on ClinicalTrials.gov Archive Site
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Lung Perfusion With Oxygenated Blood During Aortic Clamping
Lung Perfusion With Oxygenated Blood During Aortic Clamping

Pulmonary dysfunction presumably linked to an inflammatory response is frequent after cardiac operations using cardiopulmonary bypass (CPB) and pulmonary hypoperfusion.

Aim of the study: To evaluate the protective effect of continuous pulmonary perfusion with oxygenated blood during aortic crossclamping on the inflammatory response.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Postoperative Pulmonary Dysfunction
  • Procedure: lung perfusion
    see literature of proceeding
  • Procedure: no lung perfusion
    see literature of proceeding
  • Experimental: Lung perfusion
    Intervention: Procedure: lung perfusion
  • Active Comparator: no lung perfusion
    Intervention: Procedure: no lung perfusion
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
November 2012
November 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age 18-80 ys
  • Cardiopulmonary bypass procedure
  • FEV1 <80%
  • COPD >II

Exclusion Criteria:

  • Emergency cases
Both
18 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
NCT01186510
PulPer-001-Sch
No
Arndt-H. Kiessling, Johann Wolfgang Goethe University Hospitals
Johann Wolfgang Goethe University Hospitals
Not Provided
Not Provided
Johann Wolfgang Goethe University Hospitals
June 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP