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Genetic Contributions to Autism Spectrum Disorders

This study has suspended participant recruitment.
Sponsor:
Information provided by (Responsible Party):
Children's Hospital Boston
ClinicalTrials.gov Identifier:
NCT01160783
First received: July 9, 2010
Last updated: August 7, 2013
Last verified: August 2013

July 9, 2010
August 7, 2013
April 2007
December 2015   (final data collection date for primary outcome measure)
Gene expression levels [ Time Frame: At sample collection ] [ Designated as safety issue: No ]
Not Provided
Complete list of historical versions of study NCT01160783 on ClinicalTrials.gov Archive Site
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Genetic Contributions to Autism Spectrum Disorders
Genetic Contributions to Autism Spectrum Disorders

This study is working towards gaining a better understanding of the genetic and environmental factors involved in autism spectrum disorders (ASD), which includes autism, pervasive developmental disorder (PDD), and Asperger's syndrome. The investigators hope that information gained from this study will lead to new ways of diagnosing and treating ASDs.

Participation generally takes less than 2 hours to complete and travel to Children's Hospital Boston is not required. Participants are asked some questions about their medical and family history. The investigators also request permission to review medical records related to the ASD diagnosis. Finally, the investigators obtain a small blood or saliva sample in order to search for genes that may be important in understanding ASD. The investigators can arrange for the blood draw through a participant's physician or a clinical laboratory and saliva samples can be obtained through the mail. The study questions are answered via telephone or mailed questionnaires. There is no cost to participate.

Observational
Observational Model: Family-Based
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:

Whole blood, DNA and RNA and/or Saliva, DNA

Non-Probability Sample

Children with a diagnosis of an Autism Spectrum Disorder (autism, pervasive developmental disorder (PDD), or Asperger's syndrome) and their parents and/or siblings

  • Autism Spectrum Disorder
  • Autism
  • Asperger's Syndrome
  • Pervasive Developmental Disorder
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Suspended
1500
December 2015
December 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Clinical diagnosis of an Autism Spectrum Disorder (autism, pervasive developmental disorder (PDD), or Asperger's syndrome)
  • Age > 18 months
Both
18 Months and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01160783
07-04-0136
No
Children's Hospital Boston
Children's Hospital Boston
Not Provided
Principal Investigator: Ingrid A Holm, MD, MPH Children's Hospital Boston
Children's Hospital Boston
August 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP