Pressure Support During Chest Wall Compression

This study has been completed.
Sponsor:
Information provided by:
Hospital de Clinicas de Porto Alegre
ClinicalTrials.gov Identifier:
NCT01155648
First received: June 23, 2010
Last updated: July 1, 2010
Last verified: June 2010

June 23, 2010
July 1, 2010
May 2008
June 2009   (final data collection date for primary outcome measure)
Variation of mucus secretion aspirated. [ Time Frame: Two years ] [ Designated as safety issue: Yes ]
Same as current
Complete list of historical versions of study NCT01155648 on ClinicalTrials.gov Archive Site
Hemodynamic and pulmonary parameters. [ Time Frame: Two years ] [ Designated as safety issue: Yes ]
The hemodynamic and pulmonary parameters were collected: Hart rate (HH), respiratory rate (f), mean arterial pressure (MAP) and peripheral arterial saturation of oxygen (SpO2); peak inspiratory pressure (Ppeak),and Tidal volume (VT) measured in the ventilator, dynamic compliance (Cdyn calculated through the formula VT/ Ppeak - PEEP)
Same as current
Not Provided
Not Provided
 
Pressure Support During Chest Wall Compression
Increasing Pressure Support During Chest Wall Compression is Useful During Respiratory Therapy?

The purpose of this study is to compare two physiotherapy techniques: chest wall compression versus chest wall compression plus increase of 10 cmH2O in inspiratory pressure.

  1. After being placed in the supine position in bed, with head angle elevation at 30°, patients were randomized to:group 1 (G1): chest wall compression for ten minutes in chest or group 2 (G2): chest wall compression plus increase of 10 cmH2O in IP in PSV for ten minutes in chest.
  2. Clinical variables and APACHE II were registered.
  3. Parameters analyzed at the beginning (1) and at the end (2) of the protocol were: variation of peak pressure (ΔPp=Pp2-Pp1),variation of tidal volume (ΔVT =VT2-VT1), variation of dynamic compliance (ΔCdyn= Cdyn2-Cdyn1).
  4. The amount of variation of mucus secretion aspirated (ΔSa= Sa2-Sa1) at the end was also measured
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
  • Respiration, Artificial
  • Critical Care
  • Device: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.
  • Device: Chest wall compression for ten minutes in chest
  • Experimental: PSV group.
    Chest wall compression plus increase of 10 cmH2O of PSV.
    Intervention: Device: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.
  • Active Comparator: chest wall compression group
    Chest wall compression
    Intervention: Device: Chest wall compression for ten minutes in chest
Naue Wda S, da Silva AC, Güntzel AM, Condessa RL, de Oliveira RP, Rios Vieira SR. Increasing pressure support does not enhance secretion clearance if applied during manual chest wall vibration in intubated patients: a randomised trial. J Physiother. 2011;57(1):21-6.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
66
May 2010
June 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients on mechanical ventilation over 48 hours
  • With ventilatory drive
  • Hemodynamically stable MAP> 60 mmHg
  • With treatment of respiratory therapy

Exclusion Criteria:

  • Contra indication of increased positive inspiratory pressure
  • Peak pressure in the upper airway > 40 cmH2O
  • Osteoporosis diagnosis
  • Deny to participate in the study
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT01155648
07-504
No
Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
Not Provided
Principal Investigator: Silvia R Vieira, PhD Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
June 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP