Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia
The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2011 by Seoul National University Bundang Hospital.
Recruitment status was Active, not recruiting
Recruitment status was Active, not recruiting
Sponsor:
Seoul National University Bundang Hospital
Information provided by:
Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier:
NCT01152424
First received: June 24, 2010
Last updated: June 7, 2011
Last verified: June 2011
| Tracking Information | |
|---|---|
| First Received Date ICMJE | June 24, 2010 |
| Last Updated Date | June 7, 2011 |
| Start Date ICMJE | July 2010 |
| Primary Completion Date | April 2011 (final data collection date for primary outcome measure) |
| Current Primary Outcome Measures ICMJE |
The difference of FeNO in AEP and Community Acquired Pneumonia [ Time Frame: Six months ] [ Designated as safety issue: No ] |
| Original Primary Outcome Measures ICMJE |
The difference of Exhaled nitric oxide (FeNO) in Acute Eosinophilic pneumonia (AEP) and Community Acquired Pneumonia (CAP) [ Time Frame: Six months ] [ Designated as safety issue: No ] |
| Change History | Complete list of historical versions of study NCT01152424 on ClinicalTrials.gov Archive Site |
| Current Secondary Outcome Measures ICMJE | Not Provided |
| Original Secondary Outcome Measures ICMJE | Not Provided |
| Current Other Outcome Measures ICMJE | Not Provided |
| Original Other Outcome Measures ICMJE | Not Provided |
| Descriptive Information | |
| Brief Title ICMJE | Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia |
| Official Title ICMJE | Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Community Acquired Pneumonia |
| Brief Summary | Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult. |
| Detailed Description | Not Provided |
| Study Type ICMJE | Observational |
| Study Design ICMJE | Observational Model: Case Control Time Perspective: Prospective |
| Target Follow-Up Duration | Not Provided |
| Biospecimen | Not Provided |
| Sampling Method | Probability Sample |
| Study Population | All patients who visited the study hospital with bilateral pneumonic infiltration. |
| Condition ICMJE |
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| Intervention ICMJE | Not Provided |
| Study Group/Cohort (s) |
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| Publications * | Lee JE, Rhee CK, Lim JH, Lee SM, Shim YS, Lee CT, Lee SW. Fraction of exhaled nitric oxide in patients with acute eosinophilic pneumonia. Chest. 2012 May;141(5):1267-72. Epub 2011 Oct 20. |
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* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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| Recruitment Information | |
| Recruitment Status ICMJE | Active, not recruiting |
| Estimated Enrollment ICMJE | 50 |
| Estimated Completion Date | December 2011 |
| Primary Completion Date | April 2011 (final data collection date for primary outcome measure) |
| Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both |
| Ages | Not Provided |
| Accepts Healthy Volunteers | No |
| Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects |
| Location Countries ICMJE | Korea, Republic of |
| Administrative Information | |
| NCT Number ICMJE | NCT01152424 |
| Other Study ID Numbers ICMJE | FeNO in AEP |
| Has Data Monitoring Committee | No |
| Responsible Party | Sei Won Lee/ Assistant Professor, Seoul National University Bundang Hospital |
| Study Sponsor ICMJE | Seoul National University Bundang Hospital |
| Collaborators ICMJE | Not Provided |
| Investigators ICMJE | Not Provided |
| Information Provided By | Seoul National University Bundang Hospital |
| Verification Date | June 2011 |
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ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |
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