The Influence of Anterior Chamber Fluid Mediators on the Success Rate of Trabeculectomy

This study has been completed.
Sponsor:
Information provided by:
University of Cologne
ClinicalTrials.gov Identifier:
NCT01115218
First received: May 3, 2010
Last updated: April 12, 2013
Last verified: April 2013

May 3, 2010
April 12, 2013
October 2009
January 2010   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01115218 on ClinicalTrials.gov Archive Site
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The Influence of Anterior Chamber Fluid Mediators on the Success Rate of Trabeculectomy
The Influence of Anterior Chamber Fluid Mediators on the Success Rate of Trabeculectomy

The aim of the study is to investigate whether it is possible to predict the success of trabeculectomy in patients with glaucoma through the examination of mediators of wound healing in anterior chamber fluid. The success rate of trabeculectomy with mitomycin C in the literature is about 75%. This leads on the question why 25% of the patients received trabeculectomy are not sufficient treated and have not a long-term IOP reduction. Precisely this question is to be examined by the study.

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Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample

Patients from the University Eye Hospital of Cologne

  • Glaucoma
  • Trabeculectomy
  • Wound Healing
Procedure: Trabeculectomy
Trabeculectomy with mitomycin C
Glaucoma patients
Intervention: Procedure: Trabeculectomy
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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March 2012
January 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • patients with glaucoma with a trabeculectomy required
  • 60 eyes of 60 patients, The ratio of female / male is not involved.
  • Eye pressure under local therapy: 20mmHg and above (corrected with pachymetry table).
  • age of at least 18 years

Exclusion Criteria:

  • all patients not included in the group of inclusion criteria.
  • less than 50yl anterior chamber fluid could be collected during the operation.
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
NCT01115218
MeVeTra-2009
No
Arno Hueber, MD, University of Cologne
University of Cologne
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University of Cologne
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP