Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Regulation of Intraarticular and Synovium-related Biomarkers of Osteoarthritis. Effect of Acute Mechanical Joint Loading

This study has been completed.
Sponsor:
Collaborators:
The Danish Rheumatism Association
Danish Ministry of Health, Internal Affairs
Danish National Research Council
The Danish Medical Research Council
Information provided by:
Bispebjerg Hospital
ClinicalTrials.gov Identifier:
NCT01090375
First received: March 18, 2010
Last updated: NA
Last verified: March 2010
History: No changes posted

March 18, 2010
March 18, 2010
August 2008
March 2009   (final data collection date for primary outcome measure)
Not Provided
Not Provided
No Changes Posted
Not Provided
Not Provided
Not Provided
Not Provided
 
Regulation of Intraarticular and Synovium-related Biomarkers of Osteoarthritis. Effect of Acute Mechanical Joint Loading
Not Provided

In the present study the microdialysis method is used to investigate biochemical changes within and around the joint simultaneously in both the resting state and in a joint that had been subjected to exercise. The aim of the present study was, by applying the microdialysis technique, to monitor markers of cartilage breakdown and inflammation in 2 different positions of the knee (inside and in the inner part of the knee capsule) in a group of human females with knee osteoarthritis over a period of 3 hours.

Not Provided
Interventional
Phase 0
Intervention Model: Parallel Assignment
Primary Purpose: Basic Science
  • Osteoarthritis
  • Exercise
  • Other: Exercise
  • Other: Non Exercise
  • Experimental: Exercise
    Intervention: Other: Exercise
  • Placebo Comparator: Non Exercise
    Intervention: Other: Non Exercise
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
Not Provided
Not Provided
March 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • verified osteoarthritis (x-ray)of the knee, female,

Exclusion Criteria:

  • dementia, inflammatory diseases, regular pain medication
Female
55 Years to 75 Years
Not Provided
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT01090375
H-KF-306126
No
Not Provided
Bispebjerg Hospital
  • The Danish Rheumatism Association
  • Danish Ministry of Health, Internal Affairs
  • Danish National Research Council
  • The Danish Medical Research Council
Not Provided
Bispebjerg Hospital
March 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP