The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

This study has been completed.

Sponsor:

Information provided by:

Maisonneuve-Rosemont Hospital

ClinicalTrials.gov Identifier:

NCT01086176

First received: March 10, 2010

Last updated: April 26, 2010

Last verified: March 2010

History of Changes

Tracking Information
First Received Date ^ICMJE	March 10, 2010
Last Updated Date	April 26, 2010
Start Date ^ICMJE	March 2010
Primary Completion Date	April 2010 (final data collection date for primary outcome measure)
Current Primary Outcome Measures ^ICMJE (submitted: March 11, 2010)	The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%
Original Primary Outcome Measures ^ICMJE	Same as current
Change History	Complete list of historical versions of study NCT01086176 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures ^ICMJE (submitted: March 11, 2010)	The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10% The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation
Original Secondary Outcome Measures ^ICMJE	Same as current
Current Other Outcome Measures ^ICMJE	Not Provided
Original Other Outcome Measures ^ICMJE	Not Provided

Descriptive Information
Brief Title ^ICMJE	The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium
Official Title ^ICMJE	Not Provided
Brief Summary	The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.
Detailed Description	Not Provided
Study Type ^ICMJE	Observational
Study Design ^ICMJE	Observational Model: Case Control Time Perspective: Prospective
Target Follow-Up Duration	Not Provided
Biospecimen	Not Provided
Sampling Method	Non-Probability Sample
Study Population	Poeple having general anesthesia at HMR
Condition ^ICMJE	Post-tetanic Count on One Arm, the Other Arm is the Control
Intervention ^ICMJE	Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex) on one side, we do a post-tetanic count, on the other side we don't, after, we do train-of-four on both sides and check the difference
Study Group/Cohort (s)	Patient-control Intervention: Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Publications *	Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information
Recruitment Status ^ICMJE	Completed
Estimated Enrollment ^ICMJE	22
Completion Date	April 2010
Primary Completion Date	April 2010 (final data collection date for primary outcome measure)
Eligibility Criteria ^ICMJE	Inclusion Criteria: Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half Exclusion Criteria: Age >75 or <18 Neuromuscular disease difficult laryngoscopy predicted Allergy to rocuronium Malignant hyperthermia Full stomach Drugs the influence neuromuscular blockers Decision of the clinician to exclude his patient
Gender	Both
Ages	18 Years to 75 Years
Accepts Healthy Volunteers	No
Contacts ^ICMJE	Contact information is only displayed when the study is recruiting subjects
Location Countries ^ICMJE	Canada

Administrative Information
NCT Number ^ICMJE	NCT01086176
Other Study ID Numbers ^ICMJE	MaisonneuveRH-09092
Has Data Monitoring Committee	Not Provided
Responsible Party	Louis-Philippe Fortier MD Msc, HMR
Study Sponsor ^ICMJE	Maisonneuve-Rosemont Hospital
Collaborators ^ICMJE	Not Provided
Investigators ^ICMJE	Not Provided
Information Provided By	Maisonneuve-Rosemont Hospital
Verification Date	March 2010
^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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