Malaria Survey in Mbarara District, Uganda 2010

This study has been completed.
Sponsor:
Collaborator:
Medecins Sans Frontieres
Information provided by:
Epicentre
ClinicalTrials.gov Identifier:
NCT01062386
First received: February 3, 2010
Last updated: August 11, 2011
Last verified: August 2011

February 3, 2010
August 11, 2011
January 2010
February 2010   (final data collection date for primary outcome measure)
Proportion of malaria infections in children under 5 years of age [ Time Frame: January-February 2010 ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01062386 on ClinicalTrials.gov Archive Site
Proportion of families with knowledge, attitude and practice regarding malaria prevention [ Time Frame: January-February 2010 ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Malaria Survey in Mbarara District, Uganda 2010
The Epidemiology of Malaria Among Children Under Five in Mbarara District, Uganda - A Cross-sectional Population-based Survey 2010

Malaria is one of the major public health problems in Sub-Saharan Africa. In response to this threat, Roll Back Malaria (RBM) has rolled back a strategy using ACT as first line therapy for malaria episode, a wide distribution of Insecticide Treated Bednet (ITN), intermittent presumptive treatment of pregnant women and indoor residual spraying. Recent epidemiological observations suggested a decline in malaria prevalence in some countries but further evidences are still needed to confirm this evolution. The RBM strategy requires the use of reliable rapid diagnostic test (RDT) for which an operational assessment is necessary. Lastly, home-based management of malaria is also an important compound of this strategy. However, a better understanding of the actual use of antimalarial drugs, of the use of bednet and of the barrier to the use of health care is important to implement good quality strategies for malaria control.

This study is a cross-sectional community based survey made of two rounds (one in January 2010 and the second in June 2010). The general objective is to measure the prevalence of infection with Plasmodium falciparum at two periods of the year (at the moment of lowest and highest transmission based on the seasonal rainfalls) and to compare it with the prevalence estimated in 2004 after the rainy season for the same area. Specific objective are the estimation of the prevalence by age stratum, the analysis of the geographical distribution of the infection, the description of the parasitological characteristics, the assessment of three RDT, the description and the analysis of the prevention and care seek behaviours related to malaria.

The study area is the great Mbarara district located in south-west of Uganda. A three-stage cluster sampling method will be used. Spatial information will be collected with global positioning system and imported to Geographical Information System. Behaviour information will be collected through face to face interview.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:

Blood sample for:

Malaria rapid diagnostic test, Malaria Blood smear, Malaria PCR, Anopheles mosquitoes anti-saliva antibodies

Probability Sample

Children living in Great Mbarara district

Malaria
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
2320
July 2010
February 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Males and females
  • Ages 1 month to 59 months

Exclusion Criteria:

  • None
Both
1 Month to 59 Months
Yes
Contact information is only displayed when the study is recruiting subjects
Uganda
 
NCT01062386
Epicentre/Mba/2010/MalPrev
No
Carolyn Nabasumba, Epicentre
Epicentre
Medecins Sans Frontieres
Principal Investigator: Carolyn Nabasumba Epicentre
Epicentre
August 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP