Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Haukeland University Hospital
ClinicalTrials.gov Identifier:
NCT01044641
First received: January 6, 2010
Last updated: January 7, 2014
Last verified: January 2014

January 6, 2010
January 7, 2014
December 2009
May 2013   (final data collection date for primary outcome measure)
Colloid osmotic pressure [ Time Frame: 60 minuttes after wick insertion ] [ Designated as safety issue: No ]
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Complete list of historical versions of study NCT01044641 on ClinicalTrials.gov Archive Site
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Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children
Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

The purpose of this study is to identify normal values of colloid osmotic pressure in interstitial fluid and plasma in healthy children between 2 and 10 years.

Measurements of colloid osmotic pressure (COP) by sampling of interstitial fluid from subcutaneous tissue and plasma are well documented in animal models and human adult studies. COP plays a major role in transcapillary fluid balance and is valuable in fluid therapy planning in critically ill patients. There are no data regarding interstitial fluid COP values in neither sick nor healthy children. Sampling of interstitial fluid by the wick method in children who is under general anaesthesia (ear-nose-throat operations) gives the opportunity to identify normal COP values in this age group.

Observational
Observational Model: Cohort
Time Perspective: Prospective
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Retention:   Samples Without DNA
Description:

Interstitial fluid and serum

Non-Probability Sample

Secondary care clinic (ENT)

Colloid Osmotic Pressure
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
99
May 2013
May 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Children from 2 to 10 years

Exclusion Criteria:

  • Medication
  • Ongoing illness
  • Syndromes
Both
2 Years to 10 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Norway
 
NCT01044641
065816
No
Haukeland University Hospital
Haukeland University Hospital
Not Provided
Principal Investigator: Hans Joergen T Guthe, MD Hanukeland University Hospital
Haukeland University Hospital
January 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP