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The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men

This study has been completed.
Sponsor:
Collaborators:
Natural Sciences and Engineering Research Council, Canada
Mondelēz International, Inc.
Information provided by:
University of Toronto
ClinicalTrials.gov Identifier:
NCT00988377
First received: September 30, 2009
Last updated: October 1, 2009
Last verified: October 2009
History of Changes

September 30, 2009
October 1, 2009
May 2007
August 2007   (final data collection date for primary outcome measure)
Blood glucose subjective appetite Food intake at 30 min [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00988377 on ClinicalTrials.gov Archive Site
physical comfort palatability [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men
The Effect of Whey Protein on Short-term Food Intake and Post-meal Blood Glucose Response in Young Men

The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.

A randomized, cross-over design study was conducted. Whey protein preloads (10-40 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed an ad libitum pizza meal. Satiety, and blood glucose were measured at baseline and selected intervals pre- (0, 15 and 30 min) and post-meal (50, 65, 80 and 95 min).
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Prevention
  • Diabetes Prevention
  • Obesity Prevention
  • Other: dietary intervention
    whey protein 10-40 g
  • Other: water control
    Iso-volumetric (300 ml) water control (Crystal Springs, Canada)
  • Experimental: 10 g whey protein
    Intervention: Other: dietary intervention
  • Experimental: 20 g whey protein
    Intervention: Other: dietary intervention
  • Experimental: 30 g whey protein
    Intervention: Other: dietary intervention
  • Experimental: 40 g whey protein
    Intervention: Other: dietary intervention
  • Experimental: water control
    Iso-volumetric (300 ml) water control (Crystal Springs, Canada)
    Intervention: Other: water control
Akhavan T, Luhovyy BL, Brown PH, Cho CE, Anderson GH. Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults. Am J Clin Nutr. 2010 Apr;91(4):966-75. Epub 2010 Feb 17.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
16
November 2007
August 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • healthy
  • normal weight ( 18-24.9 kg/m²)
  • young aged 20-27 year old

Exclusion Criteria:

  • breakfast skippers
  • smokers
  • dieters
  • individuals with diabetes (fasting BG ≥ 7.0 mmol/L) or other metabolic diseases
Male
20 Years to 27 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Canada
 
NCT00988377
Kraft_whey protein: study 1
Yes
Dr. G. Harvey Anderson, University of Toronto
University of Toronto
  • Natural Sciences and Engineering Research Council, Canada
  • Mondelēz International, Inc.
Principal Investigator: Harvey Anderson, Ph.D. University of Toronto
University of Toronto
October 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP