Metabolome and Microbiomic in Fecal Samples (MicroMet)

This study has been completed.
Sponsor:
Information provided by:
Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT00938028
First received: July 9, 2009
Last updated: July 17, 2009
Last verified: July 2009

July 9, 2009
July 17, 2009
April 2009
May 2009   (final data collection date for primary outcome measure)
Microbiome and metabolome yield [ Time Frame: one month ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00938028 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Metabolome and Microbiomic in Fecal Samples
Fecal Samples for Metabolomic and Microbiomic Studies: Effects of Preparation and Storage

The purpose of this study is to evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.

Background

Human fecal collection for clinical or research studies usually occurs at the residence of the subject, an environment not equipped with measures to accommodate proper preparation and storage of samples for microbiome and metabolome analysis.

Aims

To evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.

Methods

Fecal samples will be collected within several minutes of voiding from healthy infants at the time of diaper change at day-care center.

Samples will be divided into 7 tubes, and subjected to different storage temperatures, before preforming microbial analysis by DNA sequencing, and metabolome analysis by H1NMR spectroscoty.

Observational
Time Perspective: Prospective
Not Provided
Retention:   None Retained
Description:

Stool samples

Non-Probability Sample

Healthy toddlers in a day care center

Infant
Not Provided
Microbiome, Metabolome, Stool, Toddler
healthy infant stool samples
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
4
May 2009
May 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • healthy
  • age 12-20 months
Both
12 Months to 20 Months
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00938028
2009p-000636
No
Harland Winter, MD, MassGeneral Hospital for Children
Massachusetts General Hospital
Not Provided
Principal Investigator: Harland Winter, MD MGH
Massachusetts General Hospital
July 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP