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Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2012 by Toronto Rehabilitation Institute.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Heart and Stroke Foundation of Canada
Information provided by (Responsible Party):
Dina Brooks, Toronto Rehabilitation Institute
ClinicalTrials.gov Identifier:
NCT00929994
First received: June 29, 2009
Last updated: November 6, 2012
Last verified: November 2012

June 29, 2009
November 6, 2012
March 2010
March 2013   (final data collection date for primary outcome measure)
Primary outcomes include improvements in cardiovascular fitness, functional capacity, and physical activity levels in individuals with TIA. This will be measured using a cardiopulmonary exercise test and a 6 minute walk test. [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00929994 on ClinicalTrials.gov Archive Site
Secondary outcome measures are plasma lipid analysis, questionnaires pertaining to quality of life, physical activity and diet diaries, and results from the Montreal Cognitive Assessment and MRI analysis. [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack
Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack

It is hypothesized that the addition of formal cardiac rehabilitation to standard care will result in long-term improvements in cardiovascular fitness and functional capacity in individuals who have suffered a transient ischemic attack (TIA) or minor stroke.

Furthermore, it is proposed that the addition of cardiac rehabilitation will influence stroke risk, physical activity participation, strength, and quality of life.

A transient ischemic attack (TIA) is defined as an episode of neurological dysfunction caused by focal brain ischemia lasting less than 24 hours. Once an individual has suffered a TIA, preventative measures can be taken to target modifiable risk factors, one of which is physical inactivity. The current proposal focuses on the use of an established model of care (cardiac rehabilitation (CR)) and applies it to those who have suffered a TIA in order to maximize physical activity and minimize risk of future cardiovascular events. This will be a one-group pre/post design study. Participants will undergo measures at baseline, 6 and 12 months (cardiovascular fitness, 6 minute walk test, quality of life, diet, strength, physical activity, and Framingham Profile stroke risk (plasma lipids, blood pressure, medication use)).

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Probability Sample

TIA

Transient Ischemic Attack
Behavioral: Cardiac Rehabilitation
Individualized cardiac rehabilitation for 12 months, including health education sessions, as well as supervised exercise classes which include aerobic and resistance training.
Exercise
Participants in this group will participate in Cardiac Rehabilitation, carrying out an exercise program which will last 12 months and combine both resistance and aerobic training.
Intervention: Behavioral: Cardiac Rehabilitation
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
40
March 2013
March 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Diagnosed with TIA
  • Three months post-TIA
  • Ability to understand the process and instructions for exercise training and provide informed consent

Exclusion Criteria:

  • Resting Blood Pressure greater than 160/100 despite medication
  • Other cardiovascular morbidity which would limit exercise tolerance (heart failure, abnormal BP responses or STsegment depression > 2 mm, symptomatic aortic stenosis, complex arrhythmias)
  • Current and extensive exercise participation
  • Hypertrophic Cardiomyopathy
  • Unstable Angina
  • Orthostatic BP decrease of > 20 mm Hg with symptoms
  • Other musculoskeletal impairments which would limit the participant's ability to walk sufficient durations
  • Pain or other co-morbidities (e.g., unclipped aneurysms, uncontrolled seizures etc.) which would preclude participation
  • Cognitive or behavioural issues that would limit participation in exercise testing and training
Both
18 Years and older
No
Contact: Dina Brooks, PhD 416-978-1739 Dina.Brooks@utoronto.ca
Canada
 
NCT00929994
Brooks - 001
No
Dina Brooks, Toronto Rehabilitation Institute
Toronto Rehabilitation Institute
Heart and Stroke Foundation of Canada
Principal Investigator: Dina Brooks, PhD Toronto Rehabilitation Institute
Principal Investigator: William E McIllroy, PhD University of Waterloo
Principal Investigator: Paul Oh, MD Toronto Rehabilitation Institute
Principal Investigator: Sandra Black, MD Sunnybrook and Women's College Health Centre
Toronto Rehabilitation Institute
November 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP