NWP06 in the Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Pfizer
ClinicalTrials.gov Identifier:
NCT00904670
First received: May 18, 2009
Last updated: April 2, 2013
Last verified: April 2013

May 18, 2009
April 2, 2013
May 2009
August 2009   (final data collection date for primary outcome measure)
SKAMP [ Time Frame: Weeks 5-6 ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00904670 on ClinicalTrials.gov Archive Site
PERMP [ Time Frame: Weeks 5-6 ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
NWP06 in the Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)
NWP06 in the Treatment of Children With ADHD: A Laboratory Classroom Study

The purpose of this study is to determine whether NWP06 is effective in the treatment of ADHD in children ages 6-12.

This is a randomized, double-blind, placebo-controlled, crossover design, optimized-dose, Phase 3 trial to evaluate the safety and efficacy of NWP06 in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients 6 to 12 years of age.

Interventional
Phase 3
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Attention Deficit Hyperactivity Disorder
  • Drug: NWP06
    Once daily liquid
  • Drug: Placebo
    Once daily liquid
  • Experimental: NWP06
    Intervention: Drug: NWP06
  • Placebo Comparator: Placebo
    Intervention: Drug: Placebo
Wigal SB, Childress AC, Belden HW, Berry SA. NWP06, an extended-release oral suspension of methylphenidate, improved attention-deficit/hyperactivity disorder symptoms compared with placebo in a laboratory classroom study. J Child Adolesc Psychopharmacol. 2013 Feb;23(1):3-10. doi: 10.1089/cap.2012.0073. Epub 2013 Jan 5.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
45
August 2009
August 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • ADHD
  • In need of pharmacological treatment for ADHD

Exclusion Criteria:

  • Other psychiatric diagnoses
  • Significant cognitive impairment
  • Chronic medical illnesses
  • Structural cardiac defects
  • Significant abnormal lab tests
  • Taking disallowed medications
  • Positive drug test
Both
6 Years to 12 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00904670
NWP06-ADD-100
No
Pfizer
Pfizer
Not Provided
Study Director: Sally A Berry, MD, PhD Pfizer
Pfizer
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP