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Predictors of Cord Blood Immunoglobin E (IgE) Levels

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2009 by Min-Sheng General Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Min-Sheng General Hospital
ClinicalTrials.gov Identifier:
NCT00902096
First received: May 13, 2009
Last updated: NA
Last verified: May 2009
History: No changes posted

May 13, 2009
May 13, 2009
April 2009
Not Provided
cord blood IgE [ Time Frame: at birth ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
Cord blood cytokines or other mediators [ Time Frame: at birth ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Predictors of Cord Blood Immunoglobin E (IgE) Levels
Not Provided

Background: Increased total serum IgE levels are a common characteristic of atopic diseases. Increased cord blood IgE levels, in conjunction with a family history of atopy, are associated with the development of allergic diseases in children. However, little is known about predictors of cord blood IgE levels.

Objective: The aim of our study was to identify predictors of cord blood IgE levels in an ongoing large birth cohort of infants with or without a family history of atopy.

Methods: Blood sampling of mothers was performed just before the delivery of newborns. Cord blood was also collected when the child was born. Maternal and cord blood was measured for IgE levels and cytokines. Questionnaires were administered after birth of the infant.

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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample

hospital and primary care clinic based study

Atopy
Not Provided
Prenatal factors
Prenatal factors to predict cord blood IgE
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
800
Not Provided
Not Provided

Inclusion Criteria:

  • Mothers in pregnancy 18 years of age or older, AND
  • Mothers able to speak Chinese.

Exclusion Criteria:

  • Infant delivered at less than 36 weeks' gestation,
  • Infant with Apgar score in 5 minutes after birth < 7,
  • Infant with a major congenital anomaly, OR
  • Infant admitted to an intensive care unit.
Both
Not Provided
Yes
Contact: Chien-Han Chen, MD 886-3-3179599 ext 2004 chinsword@yahoo.com.tw
Taiwan
 
NCT00902096
2009008
Not Provided
Chien-Han Chen, Min-Sheng General Hospital
Min-Sheng General Hospital
Not Provided
Principal Investigator: Chien-Han Chen, MD Min-Sheng General Hospital
Min-Sheng General Hospital
May 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP