Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Nerve Morphology in Diabetic Patients

This study has been completed.
Sponsor:
Information provided by:
Skane University Hospital
ClinicalTrials.gov Identifier:
NCT00856011
First received: March 4, 2009
Last updated: NA
Last verified: March 2009
History: No changes posted

March 4, 2009
March 4, 2009
December 2003
Not Provided
Nerve morphology (Fascicular area, myelinated nerve fiber density, endoneurial capillary density and subperineurial space [ Designated as safety issue: No ]
Same as current
No Changes Posted
Not Provided
Not Provided
Not Provided
Not Provided
 
Nerve Morphology in Diabetic Patients
Posterior Interosseous Nerve Pathology May Provide Novel Insights Into Both Predisposition and Potential Vascular Basis for the Development of Carpal Tunnel Syndrome in Diabetic Patients.

The underlying basis of carpal tunnel syndrome and the basis of its increased incidence in diabetes are unknown. The aim of this study was to quantified pathology in an uncompressed nerve (posterior interosseous nerve in the forearm between diabetic and non-diabetic patients with CTS.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

Biopsies of the posterior interosseous nerve

Probability Sample

Patients referred to a specialized hand clinic

  • Peripheral Neuropathy
  • Carpal Tunnel Syndrome
  • Entrapment Neuropathies
  • Diabetes Complications
Not Provided
  • 1
    Diabetic patients with carpal tunnel syndrome
  • 2
    Non-diabetic patients with carpal tunnel syndrome
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
46
April 2008
Not Provided

Inclusion Criteria

  • Diagnosis of carpal tunnel syndrome based in clinical history and symptoms
  • Confirmed by nerve conduction studies

Exclusion Criteria

  • Other focal nerve entrapments
  • Cervical radiculopathy
  • Inflammatory joint disease
  • Renal failure
  • Thyroid disorders
  • Previous wrist fracture
  • Long-term exposure to vibrating tools
  • Age under 18
Both
18 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
Sweden
 
NCT00856011
LU 508-03 (2003)
No
Niels Thomsen, MD
Skane University Hospital
Not Provided
Not Provided
Skane University Hospital
March 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP