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The Effect of Chloroquine in the Treatment of Patients With Dengue

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2009 by University of Sao Paulo.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Information provided by:
University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT00849602
First received: February 23, 2009
Last updated: NA
Last verified: February 2009
History: No changes posted

February 23, 2009
February 23, 2009
February 2008
May 2008   (final data collection date for primary outcome measure)
Duration of the disease [ Time Frame: one week ] [ Designated as safety issue: Yes ]
Same as current
No Changes Posted
Intensity and days of fever and symptoms [ Time Frame: one week ] [ Designated as safety issue: Yes ]
Same as current
Not Provided
Not Provided
 
The Effect of Chloroquine in the Treatment of Patients With Dengue
The Effect of Chloroquine in the Treatment of Patients With Dengue

The objective of this study was to evaluate the effect of chloroquine in the treatment of patients with dengue.
Not Provided
Interventional
Phase 1
Phase 2
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
Dengue
  • Drug: Placebo
    Placebo bid for three days
  • Drug: Chloroquine
    Chloroquine bid for three days
  • Placebo Comparator: 1
    Intervention: Drug: Placebo
  • Active Comparator: 2
    Intervention: Drug: Chloroquine
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
132
June 2009
May 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients suspected of having dengue disease

  • Patients were included in the study if they presented with fever and at least two other symptoms, such as:

    • headache
    • pain behind the eyes
    • muscle and bone or joint pains
    • nausea
    • vomiting
    • rash associated to dengue for less than 72 hours

Exclusion Criteria:

  • Pregnant
  • Younger than 18-years old
  • Either cardiac or neurologic disease
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT00849602
BALF-01
Yes
Benedito Antonio Lopes da Fonseca, São Paulo University Medical School at Ribeirão Preto
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo
Principal Investigator: Benedito AL Fonseca, PhD São Paulo University Medical School at Ribeirão Preto
University of Sao Paulo
February 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP