Is Carotid Intima-media Thickness Affected by A1C Variability?

This study has been completed.
Sponsor:
Information provided by:
Yonsei University
ClinicalTrials.gov Identifier:
NCT00842972
First received: February 11, 2009
Last updated: September 14, 2009
Last verified: September 2009

February 11, 2009
September 14, 2009
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Complete list of historical versions of study NCT00842972 on ClinicalTrials.gov Archive Site
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Is Carotid Intima-media Thickness Affected by A1C Variability?
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This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.

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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Probability Sample

typeII, Fluroscopy in carotid once a year during 2 years.

  • Type 2 Diabetes
  • A1C Variability
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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Inclusion Criteria:

  • type II
  • fluoroscopy in carotid once a year during 2 years

Exclusion Criteria:

  • type 1 diabetes
  • history or clinical evidence of coronary artery disease or cerebral or peripheral vascular disease
  • the presence of albuminuria (defined as 24 hour urine albumin excretion ≥ 30 mg)
  • renal dysfunction (defined as creatinine blood level ≥ 2.0 mg/dL)
  • hepatic dysfunction (defined as alanine aminotransferase and/or aspartate aminotransferase blood level ≥ 3 × upper normal limit)
  • smoking within the past 3 months prior to commencement of the study
  • use of any medication likely to alter IMT such as calcium channel blocker, thiazolidinedione, antiplatelet agent (clopidogrel, cilostazol)
  • use of glucocorticoid
  • pregnancy
  • severe concomitant disease such as cancer
  • infection
  • Cushing's syndrome
  • acromegaly, or any other disorder likely to alter glycemia
  • primary hypercholesterolemia
  • hypothyroidism or hyperthyroidism
  • use of any hormonal drugs
  • alcoholism or drug abuse
Both
34 Years to 79 Years
No
Contact information is only displayed when the study is recruiting subjects
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NCT00842972
3-2006-0005
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Ahn, Chul Woo, Gangnam Severance Hospital
Yonsei University
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Yonsei University
September 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP