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Improving Human Ovarian Transplantation

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
Israel Science Foundation
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00827476
First received: January 21, 2009
Last updated: NA
Last verified: January 2009
History: No changes posted

January 21, 2009
January 21, 2009
January 2009
January 2012   (final data collection date for primary outcome measure)
improving folliculogenesis and oocuyte maturation after ovarian transplantation [ Time Frame: 2 years ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
Not Provided
Not Provided
Not Provided
Not Provided
 
Improving Human Ovarian Transplantation
Phase 1 Study to Improve Results of Human Ovarian Transplantation

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.

Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.

Interventional
Phase 0
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Fertility Preservation
Procedure: ovarian transplantation
ovarian xenotransplantation or in vitro culture
Experimental: ovarian transplantation
tissue will be used for xenotransplantation or in vitro culture
Intervention: Procedure: ovarian transplantation
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
100
January 2015
January 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • tissue previously obtained

Exclusion Criteria:

  • no tissue available or no consent
Female
5 Years to 40 Years
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00827476
0530-08-HMO- CTIL
Yes
Ariel Revel, Hadassah Medical Organization
Hadassah Medical Organization
Israel Science Foundation
Not Provided
Hadassah Medical Organization
January 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP