The Efficacy of Nurse-Driven, Protocol Guided Ventilator Weaning in a Medical-Surgical Intensive Care Unit (ICU)
| Tracking Information | |||||
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| First Received Date ICMJE | November 5, 2008 | ||||
| Last Updated Date | November 5, 2008 | ||||
| Start Date ICMJE | December 2007 | ||||
| Primary Completion Date | June 2008 (final data collection date for primary outcome measure) | ||||
| Current Primary Outcome Measures ICMJE |
Average Length of Stay on Ventilator [ Designated as safety issue: Yes ] | ||||
| Original Primary Outcome Measures ICMJE | Same as current | ||||
| Change History | No Changes Posted | ||||
| Current Secondary Outcome Measures ICMJE |
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| Original Secondary Outcome Measures ICMJE | Same as current | ||||
| Current Other Outcome Measures ICMJE | Not Provided | ||||
| Original Other Outcome Measures ICMJE | Not Provided | ||||
| Descriptive Information | |||||
| Brief Title ICMJE | The Efficacy of Nurse-Driven, Protocol Guided Ventilator Weaning in a Medical-Surgical Intensive Care Unit (ICU) | ||||
| Official Title ICMJE | The Efficacy of Nurse-Driven, Protocol Guided Ventilator Weaning in a Medical-Surgical ICU | ||||
| Brief Summary |
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| Detailed Description | Ventilatory support is one of the most common indications for admission to ICU (1). The duration of mechanical ventilation is associated with several serious complications, increase mortality, prolong ICU stay, and increase hospital cost (7,8). Traditionally, the process of ventilator weaning is initiated and carried out my physicians. Recently, there have been few studies that supported the utility of protocol guided weaning algorithms. Its use have been associated with earlier initiation of weaning, leading to shorter ventilator time, and a trend for shorter ICU length-of-stay and lower hospital costs (1,2,4,9) Several studies have also shown the relative safety of utilizing nursing (3) and RT staff alone or in cooperation with medical staff in the weaning of patients from mechanical ventilation (1,2,6). We recently developed a nurse-driven ventilator weaning protocol for all ICUs at St. Luke's and Roosevelt hospitals. The protocol was approved by the Critical Care Committee and is implemented as of May 2007. All ICU nurses, respiratory therapists, and ICU physicians have been educated on this protocol We plan to prospectively collect data to look at length of stay on mechanical ventilation in patients weaned by nurse-driven ventilator weaning protocol. We plan to compare such data to retrospectively collected ventilator LOS data in patients weaned by physician-initiated ventilator weaning method. |
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| Study Type ICMJE | Observational | ||||
| Study Design ICMJE | Observational Model: Cohort Time Perspective: Prospective |
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| Target Follow-Up Duration | Not Provided | ||||
| Biospecimen | Not Provided | ||||
| Sampling Method | Probability Sample | ||||
| Study Population | Mechanically Ventilated Patients in Medical-Surgical ICU |
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| Condition ICMJE | Vent Weaning in Medical- Surgical ICUs | ||||
| Intervention ICMJE | Not Provided | ||||
| Study Group/Cohort (s) | 1
Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol |
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| Publications * |
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* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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| Recruitment Information | |||||
| Recruitment Status ICMJE | Completed | ||||
| Enrollment ICMJE | 215 | ||||
| Completion Date | June 2008 | ||||
| Primary Completion Date | June 2008 (final data collection date for primary outcome measure) | ||||
| Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both | ||||
| Ages | 18 Years and older | ||||
| Accepts Healthy Volunteers | No | ||||
| Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects | ||||
| Location Countries ICMJE | Not Provided | ||||
| Administrative Information | |||||
| NCT Number ICMJE | NCT00786617 | ||||
| Other Study ID Numbers ICMJE | 07-122 | ||||
| Has Data Monitoring Committee | Yes | ||||
| Responsible Party | Hassan Khouli, MD, St. Luke's Roosevelt Hospital | ||||
| Study Sponsor ICMJE | St. Luke's-Roosevelt Hospital Center | ||||
| Collaborators ICMJE | Not Provided | ||||
| Investigators ICMJE |
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| Information Provided By | St. Luke's-Roosevelt Hospital Center | ||||
| Verification Date | September 2008 | ||||
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ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |
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