Adiponectin and Insulin Resistance in Diabetic Nephropathy

This study has been completed.
Sponsor:
Collaborator:
Shanghai Jiao Tong University School of Medicine
Information provided by:
Xi’an Jiaotong University College of Medicine
ClinicalTrials.gov Identifier:
NCT00774904
First received: October 16, 2008
Last updated: October 17, 2008
Last verified: October 2008

October 16, 2008
October 17, 2008
April 2007
October 2007   (final data collection date for primary outcome measure)
GFR, HbA1c and the adiponectin concentration [ Time Frame: 6 month ] [ Designated as safety issue: Yes ]
Same as current
Complete list of historical versions of study NCT00774904 on ClinicalTrials.gov Archive Site
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Adiponectin and Insulin Resistance in Diabetic Nephropathy
Adiponectin is Positively Associated With Insulin Resistance in Subjects With Type 2 Diabetic Nephropathy and Effects by Angiotensin Type 1 Receptor Blocker Losartan

Plasma adiponectin concentration is inversely associated with renal function. There is little literature on adiponectin levels and regulation by antihypertensive medication with an angiotensin II-receptor blocker (ARB), especially in subjects with type 2 diabetes in different stage of chronic kidney disease (CKD).

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Interventional
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Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Diabetic Nephropathy
Drug: Losartan
Angiotensin II Type 1 Receptor Blockers
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
80
November 2007
October 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Type 2 diabetic nephropathy
  • CKD at stage 1~4

Exclusion Criteria:

  • Type 1 diabetes or nondiabetic renal disease
  • An elevated plasma K level.
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
China
 
NCT00774904
ADPN
Not Provided
hui min Jin, shanghai No 3 people's hospital
Xi’an Jiaotong University College of Medicine
Shanghai Jiao Tong University School of Medicine
Not Provided
Xi’an Jiaotong University College of Medicine
October 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP