Treatment for Word Retrieval Impairments in Aphasia

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2012 by Old Dominion University.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Dr. Anastasia Raymer, Old Dominion University
ClinicalTrials.gov Identifier:
NCT00764400
First received: September 30, 2008
Last updated: May 18, 2012
Last verified: May 2012

September 30, 2008
May 18, 2012
August 2008
June 2012   (final data collection date for primary outcome measure)
Daily Probe Picture Naming [ Time Frame: daily probes from three times per week for up to 3 months and one month posttreatment ] [ Designated as safety issue: No ]
Daily Probe Picture Naming [ Time Frame: daily probes from pretreatment to one month posttreatment ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT00764400 on ClinicalTrials.gov Archive Site
  • Western Aphasia Battery [ Time Frame: pre-treatment and at treatment completion ] [ Designated as safety issue: No ]
  • Boston Naming Test [ Time Frame: pretreatment and at treatment completion ] [ Designated as safety issue: No ]
  • Discourse Sample [ Time Frame: pre-treatment and at treatment completion ] [ Designated as safety issue: No ]
  • Western Aphasia Battery [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
  • Boston Naming Test [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
  • Discourse Sample [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
  • Communicative Effectiveness Index [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
  • Functional Outcomes Questionnaire for Aphasia [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
Treatment for Word Retrieval Impairments in Aphasia
Communication Outcomes for Naming Treatments in Aphasia

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Not Provided
Interventional
Phase 1
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Stroke
Behavioral: Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.
  • Experimental: Errorless Naming Treatment
    Intervention: Behavioral: Word Retrieval Treatments for Aphasia
  • Experimental: Verbal+Gestural Facilitation
    Intervention: Behavioral: Word Retrieval Treatments for Aphasia
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
16
July 2012
June 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • left hemisphere stroke >4 months earlier
  • aphasia with word retrieval impairments
  • >21 years of age right handed
  • speaker of English as the preferred language
  • >6 grade education

Exclusion Criteria:

  • history of developmental learning difficulties
  • history of prior neurological illnesses
  • chronic medical illnesses that restrict participation in speech therapy
  • alcohol or drug dependence
  • severe uncorrected impairments of vision or hearing
Both
21 Years to 90 Years
No
Contact: Anastasia M Raymer, PhD 757-683-4522 sraymer@odu.edu
Contact: Sheryl Spence 757-683-4117
United States
 
NCT00764400
R15 DC009690, 3R15DC009690, R15 DC009690
No
Dr. Anastasia Raymer, Old Dominion University
Old Dominion University
National Institute on Deafness and Other Communication Disorders (NIDCD)
Principal Investigator: Anastasia M Raymer, PhD Old Dominion University
Old Dominion University
May 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP