Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

This study has been completed.
Sponsor:
Collaborator:
MGP Ingredients, Inc
Information provided by:
Kansas State University
ClinicalTrials.gov Identifier:
NCT00687960
First received: May 22, 2008
Last updated: May 28, 2008
Last verified: May 2008

May 22, 2008
May 28, 2008
November 2006
May 2007   (final data collection date for primary outcome measure)
Post-Prandial Metabolism [ Time Frame: Early morning ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00687960 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults
Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

This study tested the effects of resistant starch type 4 on blood sugar and hunger in young adults with Type 2 diabetes.

To measure the blood glucose response, after an overnight fast, blood samples were collected before eating and at 15, 30, 45, 60, 90, and 120 minutes after each each bar. The incremental area under the curve was used to calculate the glycemic index and insulin sensitivity via minimal model.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Supportive Care
Hyperglycemia
  • Dietary Supplement: Resistant starch type 4 - raw
    Dose: 80g bar containing Resistant Starch Type 4 - raw
  • Dietary Supplement: Resistant Starch Type 4 - Cooked
    Dose: 80g bar containing Resistant Starch Type 4 - cooked
  • Dietary Supplement: Dextrose
    Dose: 7 oz of oral glucose tolerance beverage
  • Dietary Supplement: Puffed Wheat
    Dose: 80g bar containing puffed wheat cereal
  • Experimental: 1
    Resistant Starch Type 4-Raw
    Intervention: Dietary Supplement: Resistant starch type 4 - raw
  • Experimental: 2
    Resistant Starch Type 4-cooked
    Intervention: Dietary Supplement: Resistant Starch Type 4 - Cooked
  • Active Comparator: 3
    Puffed wheat
    Intervention: Dietary Supplement: Puffed Wheat
  • Placebo Comparator: 4
    Dextrose
    Intervention: Dietary Supplement: Dextrose
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
13
December 2007
May 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Apparently Healthy (not diagnosed with disease)
  • Young Adults (18-35)

Exclusion Criteria:

  • Diagnosed with diabetes or other metabolic disorders
  • Allergies to Wheat
  • Non-smokers
Both
18 Years to 35 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00687960
KSU-HML-RSt2
No
Mark Haub Ph.D., Department of Human Nutrition
Kansas State University
MGP Ingredients, Inc
Principal Investigator: Mark Haub, Ph.D. Department of Human Nutrition
Kansas State University
May 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP