Adolescent Substance Abuse: Progressive Treatment (ADAPT)

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Oregon Research Institute
ClinicalTrials.gov Identifier:
NCT00680576
First received: May 16, 2008
Last updated: February 11, 2014
Last verified: February 2014

May 16, 2008
February 11, 2014
March 2008
June 2014   (final data collection date for primary outcome measure)
Urine drug screens [ Time Frame: Pretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00680576 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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Adolescent Substance Abuse: Progressive Treatment
Not Provided

The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an "adaptive" treatment model will work better than a "fixed" treatment to reduce adolescent substance use.

Not Provided
Interventional
Phase 1
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Open Label
Primary Purpose: Treatment
Substance Abuse
  • Behavioral: CBT, Cognitive Behavioral Therapy
    Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.
  • Behavioral: FFT, Family Functional Therapy
    Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.
  • Active Comparator: 1
    Eight weeks of individual CBT for adolescents who have completed six weeks of group therapy and continue to use drugs.
    Intervention: Behavioral: CBT, Cognitive Behavioral Therapy
  • Active Comparator: 2
    Eight weeks of FFT for adolescents who have received six weeks of group therapy and continue to use drugs.
    Intervention: Behavioral: FFT, Family Functional Therapy
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
140
June 2014
June 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. 13 to 18 years if age
  2. Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence
  3. Live in the Albuquerque metropolitan area or surrounding communities
  4. Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).

Exclusion Criteria:

  1. There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures
  2. The adolescent is deemed dangerous to self or others during evaluation
  3. Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)
  4. Marijuana use is reported as being less than 13% of days in the previous 90 days.
Both
13 Years to 18 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00680576
DA023568, R01DA023568
No
Oregon Research Institute
Oregon Research Institute
Not Provided
Principal Investigator: Holly B Waldron, Ph.D. Oregon Research Institute Center for Family and Adolescent Research (ORI/CFAR)
Oregon Research Institute
February 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP