Study of Provider Computer Alerts Designed to Improve Delivery of HIV Care

This study has been completed.
Sponsor:
Collaborators:
Harvard Medical School
Massachusetts General Hospital
Information provided by (Responsible Party):
National Institute of Allergy and Infectious Diseases (NIAID)
ClinicalTrials.gov Identifier:
NCT00678600
First received: May 13, 2008
Last updated: November 19, 2013
Last verified: November 2013

May 13, 2008
November 19, 2013
September 2007
December 2008   (final data collection date for primary outcome measure)
Change in CD4 count [ Time Frame: Throughout study ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00678600 on ClinicalTrials.gov Archive Site
  • Time to repeat laboratory testing [ Time Frame: Throughout study ] [ Designated as safety issue: No ]
  • Time to follow up appointment [ Time Frame: Throughout study ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Study of Provider Computer Alerts Designed to Improve Delivery of HIV Care
Optimizing HIV Disease-Specific Provider Alerts: A Randomized Controlled Informatics Trial Comparing Electronic Health Record (EHR) vs. Non-EHR Provider Alerts

The purpose of this study is to determine whether alerts independent of the ambulatory health record are more effective in eliciting physician responses and therefore have greater impact on HIV disease outcomes than traditional static alerts.

This study will compare the effectiveness of standard and enhanced care alerts in HIV infected participants at Massachusetts General Hospital in Boston, Massachusetts.

Participants will be a part of this study for 4 years or until they are no longer followed at Massachusetts General Hospital. Participants will be assigned randomly to one of two arms. Participants assigned to Arm 1 will receive standard care, involving standard provider alerts which will be posted on the participant's health record. Participants assigned to Arm 2 will receive enhanced care, involving improved functionality. Experimental informatics-based provider alerts and support systems will be used to develop a pilot system designed to optimize delivery of HIV clinical care.

All participants will be monitored for new laboratory toxicities, suboptimal follow up, and virologic failure at their normally scheduled appointments.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Supportive Care
HIV Infections
  • Other: Standard (static) Computer Alerts
    Static Computer Alerts on Patient's EMR webpage.
  • Other: Enhanced Computer Alerts
    Population level and asynchronous alerts with enhanced functionality
  • Active Comparator: Standard (static) Computer Alerts
    Participants in this arm will be assigned to standard care. Participants will be monitored for new laboratory toxicity, suboptimal follow up, and virologic failure. Provider computer alerts will be posted on the participant's electronic health record summary page.
    Intervention: Other: Standard (static) Computer Alerts
  • Experimental: Enhanced Computer Alerts
    Participants in this arm will be assigned to the enhanced alert arm. Participants will be monitored for new laboratory toxicity, suboptimal follow up, and virologic failure. Providers will receive population and asynchronous computer alerts with improved functionality.
    Intervention: Other: Enhanced Computer Alerts
Robbins GK, Lester W, Johnson KL, Chang Y, Estey G, Surrao D, Zachary K, Lammert SM, Chueh HC, Meigs JB, Freedberg KA. Efficacy of a clinical decision-support system in an HIV practice: a randomized trial. Ann Intern Med. 2012 Dec 4;157(11):757-66. doi: 10.7326/0003-4819-157-11-201212040-00003. PubMed PMID: 23208165.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1011
December 2008
December 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • HIV infected
  • Followed in the Massachusetts General Hospital HIV clinic.

Exclusion Criteria:

Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00678600
1K01AI062435, K01AI062435
No
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Allergy and Infectious Diseases (NIAID)
  • Harvard Medical School
  • Massachusetts General Hospital
Principal Investigator: Gregory K Robbins, MD MPH Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)
November 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP