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Study of the Treatment of Burn Wounds With Antimicrobial Topical Soaks

This study has been terminated.
(Data inconclusive.)
Sponsor:
Information provided by (Responsible Party):
The University of Texas, Galveston
ClinicalTrials.gov Identifier:
NCT00675922
First received: December 26, 2007
Last updated: December 10, 2012
Last verified: December 2012

December 26, 2007
December 10, 2012
July 1995
May 2008   (final data collection date for primary outcome measure)
Infection Rate [ Time Frame: Acute hospitalization following burn injury: admission to discharge (1-20 weeks) ] [ Designated as safety issue: No ]
Percent of infections following antimicrobial topical treatment with Sulfamylon vs Silver Nitrate Soaks.
Wound healing with various topical antimicrobial solutions [ Time Frame: Admission to burn unit to 95% wound healing ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT00675922 on ClinicalTrials.gov Archive Site
Length of Hospital Stay With Various Antimicrobial Solutions for Burn Patients [ Time Frame: Admission to burn unit to discharge ] [ Designated as safety issue: No ]
  • Rate of infections with use of various antimicrobial agents on burn wounds. [ Time Frame: Admission to burn unit to 95% wound healing ] [ Designated as safety issue: No ]
  • Length of hospital stay with various antimicrobial solutions for burn patients [ Time Frame: Admission to burn unit to discharge ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
Study of the Treatment of Burn Wounds With Antimicrobial Topical Soaks
Comparing the Use of Sulfamylon 5%, Dakins 0.025%, Cerium, Silver Nitrate 5% and/or Other Topical Antimicrobial Products for the Treatment of Excised and/or Grafted Burn Wounds

Determine effectiveness of various antimicrobial solutions on burn wounds (infections, wound healing, length of hospital stay).

Patients were treated with both Sulfamylon soaks and Silver nitrate soaks on different burn areas. These two areas were then compared for incidence (percentage) of infections.

Interventional
Phase 2
Phase 3
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Burn
Drug: Sulfamylon 5% and Silver Nitrate Soaks
Application of Sulfamylon and Silver Nitrate Solution to burn wound daily
Other Names:
  • Sulfamylon
  • Silver Nitrate
Experimental: Sulfamylon 5% and Silver Nitrate Soaks
Application of Sulfamylon 5% Solution and Silver Nitrate soaked dressings to two different burned area. Sites were then monitored for infections during hospitalization.
Intervention: Drug: Sulfamylon 5% and Silver Nitrate Soaks
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
98
May 2008
May 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Burn Injury requiring excisional therapy
  • Hospitalization required until wounds are closed

Exclusion Criteria:

  • Known hypersensitivity to products
  • Outpatient treatment for burn injury
Both
up to 90 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00675922
95-096
Yes
The University of Texas, Galveston
The University of Texas, Galveston
Not Provided
Principal Investigator: David N Herndon, MD University of Texas
The University of Texas, Galveston
December 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP