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Psychotherapy for Intermittent Explosive Disorder

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00667212
First received: April 24, 2008
Last updated: June 11, 2013
Last verified: December 2010

April 24, 2008
June 11, 2013
August 2006
December 2010   (final data collection date for primary outcome measure)
  • Overt Aggression Scale - Modified (OASM) [ Time Frame: Screen Visit, Pre-Therapy visit, Therapy sessions 2, 4, 6, 8, 12, Post-Therapy Visit, 3, 6, and 12-month Follow-Up Vists ] [ Designated as safety issue: No ]
  • State-Trait Anger Expression Inventory - Trait Anger Scale [STAXI-T] [ Time Frame: Pre-Therapy visit, Therapy session 7, Post-Therapy visit ] [ Designated as safety issue: No ]
  • Intermittent Explosive Disorder Interview [ Time Frame: Diagnostic Interview, Post-Therapy Visit (Modified), 3, 6, and 12-month Follow-Up vists (modified) ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00667212 on ClinicalTrials.gov Archive Site
Behavioral aggression measures (Taylor Aggression Paradigm [TAP], Point Subtraction Aggression Paradigm [PSAP]) [ Time Frame: Pre-Therapy Visit, Post-Therapy Visit, 3, 6, and 12-month Follow-Up visits ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Psychotherapy for Intermittent Explosive Disorder
Individual Cognitive Behavioral Psychotherapy for Intermittent Explosive Disorder

The goal of this study is to examine the effectiveness two forms of psychotherapy (also known as "talk therapy" ) for individuals with anger and aggression problems. Anger and aggression are everywhere - on the road, in the schools, at little league games, at home, and at work. In this study we are testing usefulness of anger management techniques in reducing symptoms of Intermittent Explosive Disorder (IED) and impulsive, aggressive behavior.

Qualified participants will be randomly assigned to 12 1-hour sessions of either cognitive-behavioral therapy or supportive psychotherapy.

Participation in this study will require 16 visits over approximately 4 months with 3 follow-up sessions over a 12 month period. Therapy is provided at no cost and each study participant will receive a comprehensive psychological assessment. Two types of talk therapy are being offered in this study. One form of therapy focuses on thought and behaviors associated with anger and aggression. This type of therapy is known as cognitive behavioral therapy. The other type of therapy focuses on the individuals' feeling about their anger /aggression and the situations that lead to this anger. This is known as supportive therapy. The form of therapy you are given will be randomly determined (like by flipping of a coin).

Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
  • Anger
  • Intermittent Explosive Disorder
  • Behavioral: Cognitive Behavioral Therapy
    Twelve weekly therapy sessions, approximately one hour each in duration
    Other Name: Cognitive Restructuring, Relaxation, and Coping Skills Training
  • Behavioral: Supportive Psychotherapy
    Twelve weekly therapy sessions, approximately one hour each in duration
  • Active Comparator: 2
    Supportive Psychotherapy
    Intervention: Behavioral: Supportive Psychotherapy
  • Active Comparator: 1
    Cognitive Behavioral Therapy (Cognitive Restructuring, Relaxation, and Coping Skills Training: CRCST)
    Intervention: Behavioral: Cognitive Behavioral Therapy
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
60
December 2010
December 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Have problems with anger, temper outbursts, being irritable, getting in trouble at work or at home because of impulsive/aggressive behavior.
  • Between the ages of 18 and 55.
  • Meet other eligibility requirements as outlined by the research protocol.

Exclusion Criteria:

  • CHECK ON THIS
Both
18 Years to 55 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00667212
15143A
Yes
University of Chicago
University of Chicago
Not Provided
Principal Investigator: Michael McCloskey, PhD University of Chicago
University of Chicago
December 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP