Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Family Study of Lymphoproliferative Disorders

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Mayo Clinic
Information provided by (Responsible Party):
Mayo Clinic Identifier:
First received: February 20, 2008
Last updated: June 16, 2014
Last verified: June 2014

February 20, 2008
June 16, 2014
April 2004
July 2016   (final data collection date for primary outcome measure)
Risk of blood or lymphoma [ Time Frame: Ongoing ] [ Designated as safety issue: No ]
Not Provided
Complete list of historical versions of study NCT00626496 on Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
Family Study of Lymphoproliferative Disorders
Genetic Epidemiology of Lymphoproliferative Disorders

Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.

Not Provided
Observational Model: Family-Based
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA

We will collect blood samples from patients and their relatives for DNA and cytogenetic studies. A one time blood draw of 50 cc will be done.

Non-Probability Sample

Adults over the age of 18 who have a family history of a blood or lymph node disorder.

  • Lymphoma, Non-Hodgkin
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Lymphoma, B-Cell
  • Monoclonal B-Cell Lymphocytosis
  • Multiple Myeloma
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Not Provided
July 2016   (final data collection date for primary outcome measure)

At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.

18 Years and older
Contact: Emily Hallberg 1-800-610-7093
United States
489-04, U01CA118444
Mayo Clinic
Mayo Clinic
National Cancer Institute (NCI)
Principal Investigator: Susan Slager, Ph.D. Mayo Clinic
Mayo Clinic
June 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP