Korean Hereditary Breast Cancer Study (KOHBRA)

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2011 by Korean Breast Cancer Study Group
Sponsor:
Information provided by:
Korean Breast Cancer Study Group
ClinicalTrials.gov Identifier:
NCT00595348
First received: January 6, 2008
Last updated: May 9, 2011
Last verified: May 2011

January 6, 2008
May 9, 2011
November 2007
May 2012   (final data collection date for primary outcome measure)
Find out the prevalence of BRCA1/2 mutation of high risk breast cancer patients [ Time Frame: 6 years ] [ Designated as safety issue: Yes ]
Find out the prevalence of BRCA1/2 mutation of high risk breast cancer patients [ Time Frame: 3 years ] [ Designated as safety issue: Yes ]
Complete list of historical versions of study NCT00595348 on ClinicalTrials.gov Archive Site
Not Provided
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Korean Hereditary Breast Cancer Study
Korean Hereditary Breast Cancer Study
  1. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients with family history of breast/ovarian cancer.
  2. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients without family history, but high risk of hereditary cancer.
  3. To evaluate the prevalence of BRCA1/2 mutation of family member of BRCA1/2 mutation.
  4. To evaluate the prevalence of ovarian cancer of population of above 3 groups.
  1. To find founder mutation in Korean
  2. To correlation prevalence with risk evaluation
  3. To find risk factors concerning life style
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

DNA, Serum, plasma, Whole blood

Non-Probability Sample

All Medical Center including personal breast clinic, general hospital, university hospital, cancer institute in Korea

  • Breast Cancer
  • Ovarian Cancer
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
2250
May 2017
May 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Over 19 years old
  • Agree to this study
  • Breast cancer patient with family history of breast/ovarian cancer (1 subgroup)
  • Breast cancer patient; young age (<40), bilateral, male, combined ovarian (2 subgroup)
  • Family members with 1, 2 subgroups (3 subgroup)

Exclusion Criteria:

  • Under 20 years old
  • Unable to decide for oneself
Both
20 Years and older
Yes
Contact: Ku Sang Kim, M.D, AME. 82-31-219-5200 ideakims@gmail.com
Korea, Republic of
 
NCT00595348
KBCSG003, Sung-Won Kim, brca@korea.com
Yes
Sung-Won Kim, Seoul National University Bundang Hospital, Surgery
Korean Breast Cancer Study Group
Not Provided
Principal Investigator: Sung-Won Kim, M.D, Ph.D. Department of Surgery, Breast & Endocrine Service, Seoul National University Bundang Hospital
Korean Breast Cancer Study Group
May 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP