HRCT Evaluation of Airway Distensibility in Lung Transplant Recipients

This study is ongoing, but not recruiting participants.

Sponsor:

Information provided by (Responsible Party):

The University of Texas, Galveston

ClinicalTrials.gov Identifier:

NCT00584181

First received: December 20, 2007

Last updated: September 6, 2011

Last verified: September 2011

History of Changes

Tracking Information

First Received Date ^ICMJE

December 20, 2007

Last Updated Date

September 6, 2011

Start Date ^ICMJE

August 2007

Estimated Primary Completion Date

December 2011 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Not Provided

Original Primary Outcome Measures ^ICMJE

Not Provided

Change History

Complete list of historical versions of study NCT00584181 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Not Provided

Original Secondary Outcome Measures ^ICMJE

Not Provided

Current Other Outcome Measures ^ICMJE

Not Provided

Original Other Outcome Measures ^ICMJE

Not Provided

Descriptive Information

Brief Title ^ICMJE

HRCT Evaluation of Airway Distensibility in Lung Transplant Recipients

Official Title ^ICMJE

High Resolution Computed Tomographic Evaluation of Airway Distensibility in Lung Transplant Recipients: A Pilot Study

Brief Summary

Lung and heart-lung recipients at the University of Texas Medical Branch who have participated in the "Assessment of Cough Reflex in Lung Transplant Recipients" study who meet the specific study inclusion/exclusion criteria will have one study visit where they will undergo lung volume measurements, followed by high resolution CT scan of the lungs within 2 hours. After the initial CT scan, patients will be given a standard dose of Atrovent, followed thirty minutes later by repeat lung volume measurements and CT scan.

Detailed Description

Not Provided

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Observational Model: Cohort
Time Perspective: Prospective

Target Follow-Up Duration

Not Provided

Biospecimen

Not Provided

Sampling Method

Non-Probability Sample

Study Population

All patients who participated in the "Assessment of Cough Reflex in Lung Transplant Recipients" study who meet the specific inclusion/exclusion criteria for this study

Condition ^ICMJE

Lung Transplant

Intervention ^ICMJE

Not Provided

Study Group/Cohort (s)

All eligible patients will undergo the same procedures

Publications *

Not Provided

* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Active, not recruiting

Estimated Enrollment ^ICMJE

Estimated Completion Date

December 2011

Estimated Primary Completion Date

December 2011 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

lung transplant recipients >18 years of age
at least 12 months or greater from time of transplantation

Exclusion Criteria:

hemodynamic instability
hypoxemia
pneumonia
moderate or large pleural effusion
clinical evidence of acute rejection

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

United States

Administrative Information

NCT Number ^ICMJE

NCT00584181

Other Study ID Numbers ^ICMJE

07-247

Has Data Monitoring Committee

Responsible Party

The University of Texas, Galveston

Study Sponsor ^ICMJE

The University of Texas, Galveston

Collaborators ^ICMJE

Not Provided

Investigators ^ICMJE

Principal Investigator:

Alexander G Duarte, MD

University of Texas

Information Provided By

The University of Texas, Galveston

Verification Date

September 2011

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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