Use of Diffuse Optical Spectroscopy for Evaluation of the Trauma/Critically Care Patients

This study has been completed.
Sponsor:
Collaborators:
Beckman Laser Institute University of California Irvine
Volighten Scientific, Ltd.
Information provided by (Responsible Party):
Montana Compton, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT00581295
First received: December 19, 2007
Last updated: October 28, 2011
Last verified: October 2011

December 19, 2007
October 28, 2011
March 2007
April 2011   (final data collection date for primary outcome measure)
The ability to noninvasively diagnose conditions in the intensive care unit, or in battlefield conditions. [ Time Frame: 5 to 60 seconds ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00581295 on ClinicalTrials.gov Archive Site
Not Provided
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Use of Diffuse Optical Spectroscopy for Evaluation of the Trauma/Critically Care Patients
Use of Diffuse Optical Spectroscopy for Evaluation of the Trauma/Critically Care Patients

Trauma remains the leading cause of death and disability for Americans age 1-44. Trauma can cause internal bleeding, and this bleeding is often hard to detect without sophisticate tests that take time to complete and analyze.

In addition, internal bleeding, including bleeding into the lung and chest cavity, as well as other blood loss, happens in many critically ill patients. For example, for hemorrhage, it is very difficult to detect active hemorrhage and to determine optimal rates of fluid and blood resuscitation.

Diffuse optical spectroscopy has the potential to accurately assess adequacy of tissue perfusion, oxygenation, tissue oxygen extraction, and cytochrome oxidation states that may be critical to optimal treatment, end- organ preservation, and survival.

The research' want to monitor tissue perfusion and indicators of tissue damage and viability in critically ill patients by using DOS.

Non-invasive Optical Techniques DOS,near-infrared diffuse optical spectroscopy (NIR-DOS.

NIR-DOS provides functional physiologic tissue/organ information without ionizing radiation and without withdrawing any blood, in a cost-effective and rapid manner. The application of frequency-domain photon migration analysis (FDPM) to NIRS allows independent measurements of tissue absorption and scattering properties at depths of 1 cm or more below the skin surface.

Such capabilities will improve early diagnosis, detection, optimization of therapy, assessment of adequacy of resuscitation, and alteration in management plans for all of these critical conditions.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample

Trauma/Critically Care Patients

Trauma
Device: DOS
DOS
trauma
Intervention: Device: DOS
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
93
April 2011
April 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Adult age 18 years or older, male or female
  • Trauma/Critical Care patient

Exclusion Criteria:

  • Subject is not Trauma/Critical Care patient
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00581295
LAMMP DOS -RR-01192-29
No
Montana Compton, University of California, Irvine
Montana Compton
  • Beckman Laser Institute University of California Irvine
  • Volighten Scientific, Ltd.
Principal Investigator: Michael E Lekawa, M.D Beckman Laser Institute
University of California, Irvine
October 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP