Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers - Tabular View

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Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

This study is currently recruiting participants.

Study NCT00568490. Last updated on June 10, 2008. Information provided by Stanford University

This Tabular View shows the required WHO registration data elements as marked by ^†

Descriptive Information Fields

Brief Title ^†

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Official Title ^†

Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers

Brief Summary

To correlate tumor oxygenation as measured by the Eppendorf electrode with the serum level of secreted proteins known to be induced by tumor hypoxia.

Detailed Description

The endpoints of the study are

To validate the prognostic significance of OPN in H&N and lung cancer patients and to monitor its level during active therapy and follow up for cancer surveillance.
To identify a gene and protein signature for hypoxia in H&N and lung cancer patients.

Study Phase

Study Type ^†

Observational

Study Design ^†

Prospective

Primary Outcome Measure ^†

Secondary Outcome Measure ^†

Condition ^†

Head and Neck Cancer
Lip Neoplasms
Lip Cancer
Lung Cancer

Intervention ^†

Procedure: Eppendorf electrode measurements
Procedure: Tumor biopsy
Procedure: flabatomy

MEDLINE PMIDs

Links

Recruitment Information Fields

Recruitment Status ^†

Recruiting

Enrollment ^†

600

Start Date ^†

September 1998

Completion Date

Eligibility Criteria ^†

Inclusion Criteria:Newly diagnosed patients with head and neck cancer who has tumor accessible to tumor oxygenation measurement with a microelectrode.

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

Contacts ^††

Location Countries ^†

United States

Administrative Information Fields

NCT ID ^†

NCT00568490

Organization ID

SU-11052007-801

Secondary IDs ^††

15310; CA67166, 73995, ENT0016, NCT00185822

Study Sponsor ^†

Stanford University

Collaborators ^††

National Institutes of Health (NIH)

Investigators ^†

Principal Investigator:

Quynh-Thu Le

Stanford University

Information Provided By

Stanford University

Verification Date

June 2008

First Received Date ^†

December 4, 2007

Last Updated Date

June 10, 2008

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.